Cancer colorectal : le rôle controversé Université de Toulouse, Aliments & Cancer de la consommation de viande INRA ENVT, 23 Capelles, 31076 Toulouse, France. Texte remis le 12 février 1997, accepté après révision le 9 juin 1997. Tirés à part: D.E. Corpet Summary : Diet is supposed to influence the colorectal cancer etiology, but the precise causative factors are yet unknown. International ecol...

In this issue of the Journal, Schuurman et al. (1) investigate the association between several anthropometric measures and the risk of prostate cancer among approximately 60,000 male participants of the Netherlands Cohort Study. In many ways, their findings echo the results of most previous cohort and casecontrol studies on this topic in that they are largely inconclusive. As discussed by Schuu...

Oxidative DNA damage is one of the earliest detectable events in several neurodegenerative diseases, often preceding the onset of the clinical symptoms. Moreover, neurons in the adult human brain can re-enter the cell division cycle, likely allowing DNA repair. Impairments of DNA repair pathways are reported in neurons of patients suffering from one of several neurodegenative diseases and might...

Objectives: We aimed to investigate the correlation between serum IL-6 levels and the development of intervertebral disc degeneration (IDD) by conducting a case-control study and meta-analysis. Methods: Between January 2013 and December 2014, 87 IDD patients hospitalized in 307 Hospital of PLA, were regard as the case group and divided into bulging, protrusion and sequestration IDD types. The o...

The vulnerability paradigm accounts for women’s susceptibility to HIV infection being a consequence of socio-economic and cultural factors, and there is a strong need for socio-epidemiological analysis to understand and address vulnerability of Nepalese women to HIV infection. Therefore, to assess the risk factors and vulnerability of the wives of Nepalese labor migrants to HIV infection, we co...

C igarette smoking substantially increases the risk of cardiovascular disease, including coronary heart disease, stroke, sudden death, peripheral artery disease, and aortic aneurysm.' The overwhelming and consistent evidence supporting a causal role of smoking in cardiovascular disease derives from large numbers of observational analytic studies, both casecontrol and prospective cohort, in the ...

Lower respiratory tract infections are a major cause of mortality in children below the age of five years, particularly in resource-poor countries. Although advances in treatment protocols have reduced mortality rates, and improved vaccine technology has seen the development of more effective vaccines against a number of pathogens such as Streptococcus pneumoniae, the costs involved may prohibi...

Sir—We were made aware of the interesting research conducted by Sibai et al. during our literature review. In their casecontrol study they investigated the relation of war stressors to coronary artery disease (CAD) as determined by coronary angiography and in their cohort study war exposures were studied with reference to CVD mortality. We find it difficult to compare their research with ours d...

Selenium deficiency has been suggested by several studies to be associated with cancer risk. We conducted a casecontrol study in Szczecin, a region of northwestern Poland, on 86 cases of lung cancer, 87 cases of laryngeal cancer and an equal number of healthy controls. We studied the serum level of selenium and genotypes for four variants in four selenoprotein genes (GPX1, GPX4, TXNRD2 and SEP1...

This PhD consisted of a series of studies aiming at detecting genetic risk factors for Aggressive Periodontitis (AgP). AgP is a destructive disease of the periodontium affecting around 1% of the population and leading to early tooth loss. Microbiological and environmental factors are thought to act on a genetically susceptible host to determine AgP. We conducted a casecontrol association study ...