In This Issue In This Issue Rafts and the evil amyloids ipid rafts are bad news for those with Alzheimer's disease (AD). On page 113, Ehehalt et al. show that formation of the ␤-amyloid peptide (A ␤), which is tightly linked to AD, depends on the raft association of one of its creators. The creating enzyme is ␤-secretase, which cleaves the amyloid precursor protein (APP) to release a product th...

in this study organotypic adult spinal cord slices were used to investigate whether caspases could participate in the apoptosis of motor neurons. the thoracic region of spinal cord was sliced using a tissue chopper and cultured in a medium for 6h. morphological and biochemical features of apoptosis were assessed by fluorescent staining and terminal deoxynucleotidyl nick end labeling (tunel) met...