Castleman’s disease is an uncommon disease with poorly understood etiopathogenesis. It was described by Benjamin Castleman in 1954. It commonly occurs in the mediastinal nodes. Virtually any lymphnodal area can be affected. Extranodal involvement is rare and occurs in the lung, pancreas, breast, adrenals, and muscle. Castleman’s disease rarely occurs in the pelvic cavity and only 18 such cases ...

Indolent T-lymphoblastic proliferation (iT-LBP) is a recently recognized benign pathologic condition commonly associated with Castleman disease. The lymph node of this shows preserved lymphoid architecture nonclonal T-lymphoblasts in the interfollicular area. iT-LBP rare and diagnosis exclusion. As rule, it requires sophisticated techniques to exclude leukemia/lymphoma (T-LBL/L). We present an ...

Kaposi sarcoma-associated herpesvirus (KSHV) is a double-stranded DNA herpesvirus belonging to the gamma-herpesvirinae subfamily. KSHV has been associated with the development of three neoplastic diseases: Kaposi sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman disease (MCD). In this review, we discuss the three KSHV-associated malignancies, KSHV genome, latent and lyti...