BACKGROUND Multiple-drug-resistant organisms (MDROs) and Clostridium difficile (CD) are significant problems in health care. Evidence suggests that these organisms are transmitted to patients by the contaminated environment. METHODS This is a retrospective study of the implementation of ultraviolet environmental disinfection (UVD) following discharge cleaning of contact precautions rooms and ...

OBJECTIVES Due to the similarity in the clinical presentation, morphology, and course, celiac disease (CD) may be mixed up with other immunological disorders, such as multiple sclerosis (MS). CASE REPORT In a 43-year-old Caucasian male with a history of diarrhea and colics since young age, progressive sensory disturbances developed since age 18 years. At age 34, he was diagnosed as relapsing-...

A pot experiment was conducted to evaluate the effect of synthetic wastewater containing various concentrations of cadmium and chromium on Eucalyptus camaldulensis. Six month-old seedlings of E. camaldulensis were treated with Cd (II) and Cr (VI) for 18 months. Treatments were; T0: (Tap water, control), T1: 0.05 +1.0 mg L, T2: 0.10+2.0 mg L, T3: 0.20+4.0 mg L and T4: 0.40+8.0 mg L of Cd and Cr ...

The near ultraviolet (UV) circular dichroism (CD) of concanavalin A (Con A) exhibits a notable time dependence following Ca2+ binding, whereas in the far W CD region, a region characteristic of protein secondary structure, the spectrum does not change with time. Discrete conformational forms are observed in the near W CD which differ both in their inherent spectral properties and in their spect...

BACKGROUND Appropriateness criteria for the treatment of Crohn’s disease (CD) and ulcerative colitis (UC) have been developed by expert panels. Little is known about the acceptance of such recommendations by care providers. The aim was to explore how treatment decisions of practicing gastroenterologists differ from those of experts, using a vignette case study and a focus group. METHODS Seven...

MTHFR C677T is a common gene polymorphism that has been shown to be associated with hyperhomocysteinemia. Studies on the role of MTHFR in inflammatory bowel diseases (IBD) have yielded conflicting results, perhaps due in part to genetic heterogeneity. The prevalence of the MTHFR C677T variant allele varies according to Jewish subpopulations: Ashkenazi vs non-Ashkenazi. The aim of this study was...

The purpose of the present study was to evaluate the enhancement of tolbutamide (TBM) oral bioavailability and hypoglycaemic activity through complexation with beta-cyclodextrin (beta-CD) and hydroxypropyl-beta-cyclodextrin (HP-beta-CD). TBM and its freeze-dried inclusion complexes were administered to rabbits (New zealand breed; n=6), in a dose of 20 mg/kg. TMB plasma levels were measured by H...

There exists a pressing need for the identification of novel analgesics. We recently reported on new preclinical assay rapid analgesic screening based intraplantar (i.pl.) injection 10% hypertonic saline (HS) in female outbred (CD-1) mice. Herein, we characterized HS assay’s performance inbred (C57BL/6) mice, sensitivity to sex differences, and effects diurnal rhythm phase. In randomized, contr...