نتایج جستجو برای: cd31
تعداد نتایج: 3708 فیلتر نتایج به سال:
Follicular thyroid carcinoma (FTC) tends to metastasize to remote organs rather than local lymph nodes. Separation of FTC from follicular thyroid adenoma (FTA) relies on detection of vascular and/or capsular invasion. We investigated which vascular markers, CD31, CD34 and D2-40 (lymphatic vessel marker), can best evaluate vascular invasion and why FTC tends to metastasize via blood stream to re...
OBJECTIVE To examine the relation of endothelial microparticles (EMPs) with cardiometabolic risk in the community. BACKGROUND Circulating EMPs are small membrane vesicles released after endothelial cell injury. Endothelial microparticles are reportedly increased among individuals with a high burden of cardiovascular risk factors. However, prior investigations have been limited to small, highl...
BACKGROUND Osteosarcoma is the most common type of bone cancer and is notorious for its rapid progression. The Notch signaling pathway has recently been shown to be involved in osteosarcoma. As a major sheddase of Notch receptors, ADAM10 has been implicated in many types of cancers, but its role in osteosarcoma has not been investigated. Previous studies have shown that the expression of CD31 w...
BACKGROUND The aim of the study was to investigate how the expression of tumor markers p21, p27, p53, cyclin D1, EGFR, Ki-67, and CD31 influenced the outcome of advanced inoperable oropharyngeal carcinoma patients, treated with concomitant radiochemotherapy. PATIENTS AND METHODS The pretreatment biopsy specimens of 74 consecutive patients with inoperable stage IV oropharyngeal squamous cell c...
BACKGROUND The microvessel density (MVD) is often used as a quantitative parameter for angiogenesis. The aim of this study was to evaluate the three most commonly used endothelial markers of microvessels, CD31, CD34 and vWF, in benign and malignant prostatic tissue. MATERIALS AND METHODS Fifteen benign hyperplastic prostate and 54 prostate cancer specimens were immunohistochemically stained f...
BACKGROUND Intraductal papillary-mucinous neoplasm (IPMN) of the pancreas is an increasingly diagnosed entity since its definition by the World Health Organization in 1996. It has a broad clinical spectrum ranging from benign to malignant tumors. Optimum treatment is controversial and a better understanding of the development of IPMN of the pancreas and identification of potential prognostic fa...
Although it is expressed by all leukocytes, including T-, B-lymphocytes and dendritic cells, the immunoglobulin-like receptor CD31 is generally regarded by immunologists as a marker of endothelial cell lineage that lacks an established functional role in adaptive immunity. This perception has recently been challenged by studies that reveal a key role for this molecule in the regulation of T-cel...
Glioblastoma multiforme (GBM) is the most lethal type of brain tumor. The formation of abnormal, dysfunctional tumor vasculature and glioblastoma stem-like cells (GSCs) are believed to be the major components of the inability to treat these tumors effectively. We analyzed 70 glioblastoma samples by immunohistochemistry and double immunofluorescenc...
لایه اندومتریال رحم شامل جمعیتی از سلول ها است که خاصیت خود نوزایی داشته و ویژگی هایی شبیه سلول های بنیادی مزانشیمی را نشان می دهند. در این مطالعه هدف بررسی توان تمایزی سلول های بنیادی اندومتریال به رده های مختلف سلولی می باشد. سلول های اندومتریال از نمونه های بافتی بدست آمده از رحم انسان به صورت آنزیمی جداسازی شده و در محیط کشت dmem/f12 حاوی 10% سرم کشت داده شدند. بعد از پاساژ سوم سلول ها برای...
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