RECENT investigations of the conjunctival and nail-bed microcirculation indicate that certain changes in the small blood vessels and the circulating blood are frequently associated with disease. Straight, unkinked arterioles, tortuous veins, and micropools have been observed by Landau and Davis' in subjects with arteriosclerosis. Congestion of the venules and capillaries are seen in diabetes me...

Due to the fact that there is no symmetry in division of cancer cells, it important consider this asymmetrical behavior. Because heterogeneity during any therapy, not every cell killed only abolished, which sensitive particular treatment chosen. Mathematical models describe these pathways are critical for predicting proliferation The literature on mathematical modeling onset, growth, and metast...

Lactobacillus gasseri is one of the species, which has been considered as an oral probiotic. The probiotic characters, e.g., aggregation and adhesion abilities, may be affected by changes in environment. This study aimed to investigate effect cell surface components, some enzymes, pH, sugars, ions on (auto- coaggregation) abilities L. ability adhere epithelial cells. control group contained bac...

We previously found that a neutrophil serine protease, cathepsin G, weakens adherence to culture substrates and induces E-cadherin-dependent aggregation of MCF-7 human breast cancer cells through its protease activity. In this study, we examined whether aggregation is caused by degradation of adhesion molecules on the culture substrates or through an unidentified mechanism. We compared the effe...

The frequency dependence of the ultrasonic backscattering coefficient (BSC) was studied to assess the level of red blood cell (RBC) aggregation. Three monoelement focused wideband transducers were used to insonify porcine blood sheared in a Couette flow from 9 to 30 MHz. A high shear rate was first applied to promote disaggregation. Different residual shear rates were then used to promote forma...

The burn disease is found to be accompanied by increasing of the level of oxidized proteins of blood serum. We studied the influence of albumin oxidation rate on aggregation of platelets and erythrocytes, disaggregation of erythrocytes. The changes of blood cells aggregation associated with oxidation rate of albumin were found. Possible mechanisms of these effects are discussed.

This paper presents a fluid-particle interaction algorithm using the distributed Lagrange multiplier based fictitious domain method. The application of this method to the numerical investigation of motion and aggregation of red blood cells in two-dimensional microvessels is discussed. The cells are modelled as rigid biconcave-shaped neutrally buoyant particles. The aggregating force between two...

protein aggregation is a problem in biotechnology. high temperature is one of the most important reasons to enhance enzyme inactivation and aggregation in industrial systems. this work focuses on the effect of tio2 and sio2 nanoparticles on refolding and reactivation of lysozyme. in the presence of tio2 and sio2 nanoparticles, after enzyme heat treatment at 98◦c for 30 min, not only aggregates ...