Flood defence maintenance strategies require understanding of the time-dependent behaviour of flood defences. Quantitative risk and reliability methods provide a rational decision-making basis for flood defence management. Failure mechanisms influencing the flood defence reliability are expressed by a limit state equation and organised in a fault tree. One or more random variables in the limit ...

machine-part family formation is one of major applications of group technology (gt). the machine cell formation problem in cellular manufacturing system (cms) involves the decomposition of the manufacturing system into machine cells. part families are identified such that they are fully processed within a machine cell. the problem of cell design is a very complex task with wide ranging implicat...

Drosophila use small-interfering RNA mechanisms to limit the amplification of viral genomes. However, it is unclear how small RNA interference components recognize and separate viral from cellular RNA. Dnmt2 enzymes are highly conserved RNA methyltransferases with substrate specificity towards cellular tRNAs. We report here that Dnmt2 is required for efficient innate immune responses in Drosoph...

In this paper we present an environment for evaluating self-healing mechanisms in survivable networks. The work is based on the thesis that system level requirements of integrity and availability can be inherently conflicting, and that the type and level of defence in each particular network should be determined in relation to the particular network’s characteristics. The study shows that defin...

Magnesium deficiency (MgD) has been shown to impact numerous biological processes at the cellular and molecular levels. In the present review, we discuss the relationship between MgD and oxidative stress (OS). MgD is accompanied by increased levels of OS markers such as lipid, protein and DNA oxidative modification products. Additionally, a relationship was detected between MgD and a weakened a...

The longstanding biotic interactions hypothesis predicts that herbivore pressure declines with latitude, but the evidence is mixed. To address gaps in previous studies, we measured herbivory and defence in the same system, quantified defence with bioassays, and considered effects of leaf age. We quantified herbivory and defence of young and mature leaves along a continental gradient in eastern ...

The Intelligent Medical Diagnosis System (IMDS) has been targeted by the cyber attackers, who aim to damage Healthcare Critical National Infrastructure (CNI). This research is motivated recent attacks happened worldwide that have resulted in compromise of medical diagnosis records. study was conducted demonstrate how IMDS could be attacked and records compromised (i.e. heart disease) suggest a ...