Olive products, such as oils, olives and leaves infusions, have been used in the past to treat many health problems. This study aims to develop a methodology for maximizing the efficiency of extraction of polyphenols from olive leaves. For this purpose, two experimental design approaches (a central composite design (CCD) and a mixture design) have been used. The optimal extraction parameters ob...

The objectives of this work were to develop a new technique for lycopene microencapsulation by spray drying using dehumidified air as drying medium and to determine optimum operating conditions. A two-step optimization procedure was used. The encapsulation variables were selected in accordance with the PlackettBurman experimental design and were further optimized via response surface methodolog...

thermal cracking of a heavy liquid hydrocarbon was performed in a laboratory scale tubular reactor. central composite design (ccd), was used as an experimental design method. the design variables were coil outlet temperature (cot), feed flow and rate steam ratio. maximum yield of ethylene was 30.37 wt% at cot, residence time and steam ratio of 869oc, 0.208 s and 1.22 g/g, respectively. maximum ...

Hydrometallurgical facilities processing sulfide based ores produce waste residues in the form of sludges that contain concentrations of metals, as well as metal sulfides. As a part of the waste characterization and risk assessment process, a statistical design of experiment was used to assess the significant factors and interactions in the residue leaching process. Two shake flask experiments,...

The nutritional medium requirement for alkaline protease production was optimized by newly isolated Bacillus amyloliquefaciens B7. The variables significantly influencing the protease activity were screened through one-factor-at-a-time experiments and Plackett–Burman design, by which fructose and yeast extract were identified as the most significant variables. The steepest ascent method was emp...

The success of the thixoforming process depends on the possibility to confer to material, when it is found in the semisolid state, a microstructure characterized by globular particles of solid phase surrounded by a continuous film of liquid phase; such microstructure is obtainable through particular thermo-mechanical treatments. In the present research, in order to optimize the influence of pro...

ABSTRACT Six Sigma is a widely used moniker to represent a set of design and manufacturing techniques, the aggregate of which should effectively improve quality and lower cost. Six Sigma implies that six standard deviations of performance should be maintained between the performance mean and the closest specification limit. When multiple performance attributes must be satisfied, aggregation tec...

A statistical experimental design was employed to optimize factors that affect the production of hydrogen from the glucose contained in pineapple waste extract by anaerobic mixed cultures. Results from Plackett-Burman design indicated that substrate concentration, initial pH and FeSO4 concentration had a statistically significant (p ≤ 0.05) influence on the hydrogen production potential (Ps) an...

Biosorption of Acid Yellow (AY 17) and Acid Blue (AB 25) were investigated using a biomass obtained from brewery industrial waste spent brewery grains (SBG). A 2 full factorial response surface central composite design with seven replicates at the centre point and thus a total of 31 experiments were employed for experimental design and analysis of the results. The combined effect of time, pH, a...

Direct fermentation of 226 white rose tapioca stem to ethanol by Fusarium oxysporum was studied in a batch reactor. Fermentation of ethanol can be achieved by sequential pretreatment using dilute acid and dilute alkali solutions using 100 mesh tapioca stem particles. The quantitative effects of substrate concentration, pH and temperature on ethanol concentration were optimized using a full fact...