Depletion of mineral reservoirs along with health and environmental concerns have led to a greater focus on bio-lubricants. The purpose this study was analyze optimize the reaction conditions transesterification process for cotton biolubricant synthesis by using Response Surface Methodology (RSM). In RSM, Rotatable central composite design selected examine effect input factors yield bio-lubrica...

Cutting tests were conducted to medium carbon steel using HSS tools with cutting fluid. The experimental design used was based on response surface methodology (RSM) using a central composite design. Chips were collected at different machining conditions and thickness and microhardness measurements taken and analyzed using “DESIGN EXPERT 7” experimental design software. Mathematical models of th...

The development of a lactose-free beverage comes as a new feeding alternative to a product with excellent nutritional and functional characteristics to individuals with food restrictions related to milk. Thus, this study aimed to develop a cashew nut beverage with added mango juice and prebiotic substances by means of evaluating its sensory characteristics and physicochemical optimization. A 22...

Abstract The current study explores a design and development of the simple, fast, green selective novel method UPLC to quantify pitavastatin ezetimibe simultaneously. combined approach Green Analytical Method with Quality by Design-based risk assessment was done using Ishikawa fishbone diagram followed rotatable central composite used for optimization. optimal chromatographic separation attaine...

abstract: aqueous enzymatic extraction of oil from pistacia khinjuk was performed using cellulase. the central composite design was used to optimize the parameters that are significant to the process. the influence of three regressors on the percentage of oil recovery from seed was evaluated using second-order polynomial multiple regression model. analysis of variance showed a high coefficient ...

Many volatile compounds generated during the thermal processing of milk have been associated with cooked, stale, and sulfurous notes in milk and are considered as off-flavor by most consumers. A headspace solid-phase microextraction (HS-SPME)/gas chromatographic technique for the quantitative analysis of thermally derived off-flavor compounds was developed in this study. The extraction temperat...

The first experiment was a central composite rotatable design with calculated calcium levels of 6.2, 7.0, 9.0, 11.0, and 11.8 g/kg diet and total phosphorus levels of 5.2, 6.0, 8.0, 10.0, and 10.8 g/kg diet (2.8 g phytin-P/kg by analysis). This design involved three replicates for each rotatable point and fifteen replicates of the central point. The second experiment was a 4 x 4 factorial desig...

C-phycocyanin from Spirulina platensis was purified in aqueous two-phase systems (ATPS) of polyethylene glycol (PEG)/potassium phosphate, varying the molar mass of the PEG. Results using a full factorial design showed that an increase in the concentration of salt and decrease in the concentration of PEG caused an increment in the purification factor for all the ATPS studied. Optimization of the...