The purpose of this study was to evaluate the stress distribution in a maxillary central incisor restored with various post-core applications. The study used a three-dimensional finite element method. The tooth was assumed to be endodontically treated with a porcelain crown. Two different sizes of Flexi-post, Cera-post, and Composipost were compared for 200 N palatal and incisal loads. It was d...

The domain architecture of a large RNA can help explain and/or predict folding, function, biogenesis and evolution. We offer a formal and general definition of an RNA domain and use that definition to experimentally characterize the rRNA of the ribosomal small subunit. Here the rRNA comprising a domain is compact, with a self-contained system of molecular interactions. A given rRNA helix or ste...

We demonstrate that the 1D cylindrical version of the Grad-Shafranov equation is more rich than classical self-similar ones, and more suitable for the astrophysical jets we observe. In particular, it allows us to describe the central (and, hence, the most energetic) part of the flow. Both relativistic and non-relativistic versions are discussed. It is shown that taking into account the finite p...

We evaluate the contribution of natural variability to the modern decrease in foraminiferal δ18O by relying on a 2200-yr-long, high-resolution record of oxygen isotopic ratio from a Central Mediterranean sediment core. Pre-industrial values are used to train and test two sets of algorithms that are able to forecast the natural variability in δ18O over the last 150 yr. These algorithms are based...

Ankylosing spondylitis (AS) is an inflammatory disorder of unknown cause that primarily affects the axial skeleton. Neurological manifestations of AS are usually related to spinal deformities. Previous studies of the paraspinal muscles of AS patients showed muscle fiber atrophy, and core fibers. On the other hand, central core disease (CCD) is a genetic condition that primarily involves the ske...

Consistent chromosomal rearrangements are found in a large number of hematopoietic tumors. In many cases, these rearrangements disrupt genes whose normal function is required for the proper development of blood cells. Excellent examples are the chromosomal rearrangements t(8;21)(q22;q22), t(12;21)(p13;q22), and inv(16)(p13q22) that disrupt two of the genes encoding a small family of heterodimer...

Central core disease (CCD) is a dominantly inherited congenital myopathy allelic to malignant hyperthermia (MH) caused by mutations in the RYR1 gene on chromosome 19q13.1. Eleven individuals with RYR1 mutations are described. Four index cases showed features consistent with a congenital myopathy (hypotonia, delayed motor milestones, and skeletal abnormalities including congenital hip dislocatio...

Objectives: To investigate the clinical and pathological characteristics of central core disease (CCD) in China. Methods: A retrospective analysis was performed on the clinical data of 40 patients with CCD who presented at our department or other hospitals from 1986 to 2013. Muscle histochemical staining was used to study the muscular pathological characteristics of patients with CCD. Results: ...

We have synthesized three-dimensional self-assembled ZnO-based nanoscale heterostructures through the addition of alloying elements (In or Sn) during the vapor phase transport and condensation deposition process. Each threedimensional nanoscale heterostructure consists of a faceted nanowire core, with side branches (nanoribbons or nanorods) emanating from facets of the central nanowire core. Th...