Poor penetration of vancomycin into Central Nervous System (CNS) can lead to treatmentfailure. The aim of this study was to evaluate and compare CSF concentration and serumpharmacokinetics of high dose vancomycin by continuous infusion vs. intermittent infusion inpost neurosurgical meningitis patients. Twenty patients were divided into two groups. Patientsin intermittent infusion group received...

Objective and Importance: Developmental venous anomalies (DVAs) are common congenital anomalies of intracranial venous drainage. In general, it is felt that DVAs replace the normal venous drainage system and, unless associated with another lesion such as a cavernous malformation, should not produce symptoms. The present case raises important questions regarding the potential for DVAs to become ...

conclusions we think one of the influential factors for leading a guidewire and catheter into a nominated vein may be the left sided bevel of the needle at the time of internal jugular vein needle and catheter insertion. we were required to continue going towards the subclavian vein and accidentally turned into the left internal mammary vein. introduction central venous catheter placement is a ...

The ethanol extract of the flowering top of Rosa damascena (Rosaceae) was assessed for neuropharmacological activities in mice using a number of experimental models. It significantly prolonged the pentobarbitone-induced sleeping time in mice, and showed mild to moderate central nervous system depressant activity when assessed by the hole cross and the open field tests in mice model when given...

The entity of "neurogenic hypertension" is defined as arterial hypertension caused explicitly by derangement of the intricate network of the central nervous system. Among 193 cases of cranial rhizopathies operated on between 1984 and 1995 at this center, 5 cases of established arterial hypertension with concomitant rhizopathies also underwent ventrolateral medullary decompression. The elev...

Recent reports have emerged suggesting that multiple sclerosis (MS) may be due to abnormal venous outflow from the central nervous system, termed chronic cerebrospinal venous insufficiency (CCSVI). These reports have generated strong interest and controversy over the prospect of a treatable cause of this chronic debilitating disease. This review aims to describe the proposed association between...

central venous catheter (cvc) insertion is a practical way to assess patients hemodynamic specially in cardiovascular surgery but this relatively simple junior level procedure is not risk free and its common reported complications include; pneumothorax, hydrothorax, hemothorax, local hematoma, cardiac tamponade, vascular injury, thrombosis, embolism, and catheter disruption. here in this articl...

conclusions the management was successful and this is an avoidable complication and several precautions are explained to avoid this. case presentation an 11-year-old male presents with inadvertent retention of guidewire during cvc. introduction retention of a guidewire is one of the rare but potentially serious complications of central venous catheterization (cvc).

Retrograde pyramidal tract degeneration has been described only very rarely in the human central nervous system. In most of these cases the thoracic or cervical corticospinal tracts were shown to have degenerated following long-standing, lower spinal cord lesions. In a 67 year old man, who lived 2 years following the rupture of a mid-cervical cavernous angioma, we observed such degeneration whi...

INTRODUCTION Intramedullary cavernous angioma (ICA) is a rare lesion of the spinal cord, representing only 3% - 5% of central nervous system lesions. The coexistence of trigeminal neuralgia and refractory itch is very rarely encountered in clinical practice. To our knowledge, a report of an ICA with trigeminal neuralgia and local neuropathic itch has never been published to date. Thus, we prese...