OBJECTIVES To study cerebral blood flow and cerebral oxygen consumption in severe head-injured children and also to assess the effect of hyperventilation on regional cerebral blood flow. DESIGN Prospective cohort study. SETTING Pediatric intensive care unit at a tertiary-level university children's hospital. PATIENTS Twenty-three children with isolated severe brain injury, whose admission...

BACKGROUND Moyamoya disease causes progressive occlusion of the supraclinoidal internal carotid artery, and middle, anterior, and less frequently the posterior cerebral arteries, carrying the risk of stroke. Blood flow is often partially reconstituted by compensatory moyamoya collaterals and sometimes the posterior circulation. Cerebral revascularization can further augment blood flow. These ch...

Twenty patients with aneurysms of the internal carotid artery underwent temporary clamping, in turn, of the internal and then the common carotid artery. Cerebral blood flow, internal carotid artery pressure, and the EEG were recorded to assess the probability of cerebral ischaemia after permanent ligation. With this method of monitoring the cerebral circulation, 17 of the 20 patients had a perm...

Using positron emission tomography in nine patients with minor strokes, unilateral internal carotid artery occlusion, and good collateral circulation through the anterior portion of the circle of Willis, we analyzed regional cerebral blood flow, cerebral metabolic rate of oxygen, oxygen extraction fraction, and cerebral blood volume. These studies allowed quantification of the regional hemodyna...

Regional cerebral blood flow was studied by means of the 133Xe inhalation method in 26 untreated and 10 treated patients with essential hypertension. The untreated subjects were divided into newly and previously diagnosed groups to assess the relation between regional cerebral blood flow and the duration of hypertension. The overall flow reduction was more marked in the frontal and temporal reg...

PURPOSE Several different anti-hypertensive regimens have been introduced for the prevention of systemic hyperdynamic responses after electrically induced seizures. In the present study, the effects of anti-hypertensive medications on cerebral circulation were studied. METHODS Systemic blood pressure was controlled by several anti-hypertensive medications, nicardipine, prostaglandin EI, alpre...

Psychological status monitoring with cerebral blood flow (CBF), EEG and EOG measurements are attempted. Through experiments, it is confirmed that the proposed method for psychological status monitoring is valid. It is also found correlations among the amplitudes of peak alpha and beta as well as gamma frequency of EEG signals and EOG as well as cerebral blood flow. Therefore, psychological stat...

BACKGROUND AND PURPOSE Hemodynamic information obtained by assessing cerebral vasoreactivity is of clinical interest and may have prognostic significance in patients with occlusive carotid disease. The aim of this study was to compare the results of transcranial Doppler and regional cerebral blood flow studies when used to assess cerebral vasoreactivity. METHODS Blood flow velocities in both ...

affected by changes in systemic arterial blood pressure. J Neurosurg 44: 12-15, 1976 33. Flohr H, Poll W, Brock M: Regulation of spinal cord blood flow. 40. In: Russell RWR (ed.): Brain and blood flow. Pitman, London, 406-409, 1971 41. 34. Bayliss WM: On the local reaction of the arterial wall to changes of internal pressure. J Physiol 28: 220-231, 1902 35. Youmans JR: Cerebral blood flow in cl...

AIM To study continuously cerebral blood flow velocity in the middle cerebral artery before, during, and after tube feeding in neonates. METHOD Cerebral blood flow velocity was measured in 14 neonates using a Doppler ultrasound device. Blood pressure, respiration, and oxygen saturation were monitored. RESULTS Mean blood flow velocity decreased from 37 cm/s before feeding to 33 cm/s (P < 0.0...