Numerous studies have suggested that Cancer Initiating Cells (CIC) can be identified/enriched in cell populations obtained from solid tumors based on the expression of cell surface marker proteins. We used early passage primary cervix cancer xenografts to sort cells based on the expression of the intrinsic hypoxia marker Carbonic Anhydrase 9 (CA9) and tested their cancer initiation potential by...

Introduction : Quality of life (QOL) has become an important part the medical decision along with efficacy and safety treatment. Cancer is a chronic disease that affects quality patients from which idea evaluating QOL treated in service. This descriptive cross-sectional study carried out at Mohamed VI center for treatment cancers Ibn Rochd Hospital Casablanca over period one year. Results In ou...

Objectives: Locally advanced cervix cancer represents a therapeutic challenge with a delicate balance between effect and toxicity. Consequently, there is an obvious need for new prognostic parameters with a perspective of a more individualized treatment. The aim of the present study was to evaluate the possible prognostic importance of epidermal growth factor receptor and cyclooxygenase-2 expre...

Lymphoepithelioma-like carcinoma (LELC) of the uterine cervix is a rare type cervical cancer. The etiopathogenesis LELC involves consideration human papillomavirus (HPV) and Epstein–Barr virus infection. We present case 57-year-old female diagnosed with unique HPV-59 absence virus, which characteristic for European women. treatment included radical hysterectomy nerve-sparing hysterectomy, has n...

studies undertaken during the last 5 years in the babol research station of the institute of public health research, teheran university, with the collaboration of the international agency for research on cancer in the caspian littoral and ardabil area in the north of iran has indicated the presence of cancer in 48 different sites. the five more prevalent types of cancer found in that area in or...

gammagraphy may be normal or show multiple small, peripheral repletion defects. The diagnosis of pulmonary tumor embolism requires finding tumor cells in the lung vasculature. Cervical cancer is the second most frequent cause of morbidity and mortality related with cancer among women in developing countries: 371,200 new cases each year, with a 50% mortality rate. The incidence of invasive cervi...

INTRODUCTION Genital cancers benefit from standardized treatment plans which include: surgery and radio chemotherapy.Lately, treatments involving thermal ablations have entered the clinical use, as they destroy the tumors by the use of different energy sources. Our study aims at establishing a precise role of RFA in current treatment protocols of cancer of the uterine cervix. MATERIAL AND MET...

AIMS The molecular mechanisms of the tumorigenesis and recurrence of cervical cancer are poorly understood. The objective of this study was to analyze the expression of phosphorylated c-Src (phospho-c-Src) and its clinical significance in human cervical cancer. METHODS The expression of phospho-c-Src was determined by immunohistochemistry in a total of 127 cervical specimens including 20 norm...

BACKGROUND According to the definition by the International Agency for Research on Cancer (IARC), primary multiple neoplasms are two or more neoplasms of different histopathological build in one organ, or two or more tumors occurring in one patient, regardless of the time of their occurrence (synchronic - up to 6 months, metachronous - after 6 months), coming from an organ or a tissue and not b...

•Treatment of stage 1A1 cancer of the cervix often involves preservation of the corpus.•Rarely metastasis to the corpus can occur in these cases.