This research focuses on obtaining the behavior of chemical compounds with respect to their molecular weight and optimization energy based variation in properties organic carbon links. Here, behavioral analysis is used application a metal framework denote high-grade compounds. The grade was selected essential measure weight, turn, depicts stability material. Computation performed Avogadro softw...

The emergence of multidrug-resistant Staphylococcus aureus (S. aureus) makes the treatment of infectious diseases in hospitals more difficult and increases the mortality of the patients. In this study, we attempted to identify novel potent antibiotic candidate compounds against S. aureus dihydrofolate reductase (saDHFR). We performed three-step in silico structure-based drug screening (SBDS) ba...

The Amazing and Versatile Carbon – Chemical basis for life With an atomic number of 6, Carbon is the 4th most abundant element in the Universe by mass after (Hydrogen Helium and Oxygen). It forms more compounds that any other element, with almost 10 million pure organic compounds. Abundance, together with the unique diversity of organic compounds and their unusual polymer forming ability at the...

Trachyspermum copticum is one of the most important Iranian Apiaceae species which is widely distributed in the northern region of Iran. In this study, chemical compounds, anti-tumor and antibacterial activities of T. copticum essential oil were evaluated. The essential oil obtained by Clevenger apparatus and then the chemical composition was analyzed by GC-MS. Antibacterial activity of essenti...

An automated fluorescence microscopy assay using a nontoxic cholesterol binding protein, toxin domain 4, (D4), was developed in order to identify chemical compounds modifying intracellular cholesterol metabolism and distribution. Using this method, we screened a library of 1,056 compounds and identified 35 compounds that decreased D4 binding to the cell surface. Among them, 8 compounds were al...

The chemical composition of carbonaceous aerosols collected during the LBA-SMOCC field experiment, conducted in Rondônia, Brazil, in 2002 during the transition from the dry to the wet season, was investigated by a suite of state-of-the-art analytical techniques. The period of most intense biomass burning was characterized by high concentrations of submicron particles rich in carbonaceous materi...