نتایج جستجو برای: chemical safety

تعداد نتایج: 632559  

Journal: :Chemical research in toxicology 2007
F Peter Guengerich James S MacDonald

Toxicology can no longer be used only as a science that reacts to problems but must be more proactive in predicting potential human safety issues with new drug candidates. Success in this area must be based on an understanding of the mechanisms of toxicity. This review summarizes and extends some of the concepts of an American Chemical Society ProSpectives meeting on the title subject held in J...

2015
Diana M. Hendrickx Hugo J. W. L. Aerts Florian Caiment Dominic Clark Timothy M. D. Ebbels Chris T. A. Evelo Hans Gmuender Dennie G. A. J. Hebels Ralf Herwig Jürgen Hescheler Danyel Jennen Marlon J. A. Jetten Stathis Kanterakis Hector C. Keun Vera Matser John P. Overington Ekaterina Pilicheva Ugis Sarkans Marcelo P. Segura-Lepe Isaia Sotiriadou Timo Wittenberger Clemens Wittwehr Antonella Zanzi Jos Kleinjans

MOTIVATION The field of toxicogenomics (the application of '-omics' technologies to risk assessment of compound toxicities) has expanded in the last decade, partly driven by new legislation, aimed at reducing animal testing in chemical risk assessment but mainly as a result of a paradigm change in toxicology towards the use and integration of genome wide data. Many research groups worldwide hav...

Journal: :Journal of Industrial & Engineering Chemistry 1916

Journal: :Advances in Chemical Engineering and Science 2015

Journal: :Stavební obzor - Civil Engineering Journal 2018

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