نتایج جستجو برای: chemotypes
تعداد نتایج: 676 فیلتر نتایج به سال:
Article history: Received 2 October 2008 Accepted 22 October 2008 0957-4166/$ see front matter 2008 Elsevier Ltd. A doi:10.1016/j.tetasy.2008.10.024 * Corresponding author. E-mail address: [email protected] (S. N Novel multifunctional chemotypes based on a-tetralone, a-indanone, and chromanone have been synthesized by a chemo-enzymatic approach by applying an enzymatic irreversible tr...
The discovery of new allosteric sites generates opportunities for the identification of novel pharmaceuticals and increases our understanding of basic biological processes. Increasingly, allosteric sites are being discovered in various families of proteins by several methods, paving the way for the development of entirely new classes of drugs with a wide range of chemotypes. New allosteric site...
Inhibition of protein-protein interactions (PPIs) represents a major challenge in chemical biology and drug discovery. α-Helix mediated PPIs may be amenable to modulation using generic chemotypes, termed "proteomimetics", which can be assembled in a modular manner to reproduce the vectoral presentation of key side chains found on a helical motif from one partner within the PPI. In this work, it...
Identification of Deoxynivalenol- and Nivalenol-Producing Chemotypes of Gibberella zeae by Using PCR
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید