Delhi reports highest magnitude of risks for males and Chennai for females in all cancers combined during childhood period. Significant increase in trends of childhood cancer risk detected for all sites combined in Chennai for males and in Mumbai for females. The trends observed may likely to give an insight into further understanding of childhood cancer etiology. L Satyanarayana, Smita Asthana...

When treating childhood acute lymphoblastic leukemia (ALL), secondary neoplasms are a significant long term problem. Radiation is generally accepted to be a major cause of the development of secondary neoplasms. Following treatment for ALL, a variety of secondary tumors, including brain tumors, hematologic malignancies, sarcomas, thyroid cancers, and skin cancers have been reported. However, ol...

For many years, fruit and vegetables have been thought to be protective against various forms of adult cancers and, more recently, a number of studies have investigated specific micronutrients, particularly those taken in their supplemental form. A similar trend has been seen in research into the aetiology of childhood cancers, about which little is known despite decades of research. There has ...

Ewing's sarcoma (ES) is a rare tumor that is most common in children and young adults. Late effects of ES therapy include second cancers, a tragic outcome for survivors of such a young age. This paper will explore the frequencies and types of malignancies that occur after ES. Additionally, it will review how second malignancies have changed with the shift in treatment from high-dose radiation t...

Cancers diagnosed in children younger than 15 are increasing at about one percent per year in the U.S.[1] Cancers are now the second leading cause of death among children (after accidents). An estimated 7800 children in the U.S. were diagnosed with new cancers in 1995.[2] Part of this increase results from better diagnosis and better recording of cases by state and federal agencies, but "taken ...

Tracking incidence or prevalence of diseases and using that information to target interventions is a well-established strategy for improving public health. The need to track environmentally mediated chronic diseases is increasingly recognized. Trends in childhood illnesses are 1 element of a framework for children's environmental health indicators, which also includes trends in contaminants in ...

would have been missed. Further, ethnic differences in incidence trends have only been observed in childhoodALLand are not present in other childhood cancers (eg, childhood brain tumors), suggesting that changes in ethnic classification are unlikely to be solely responsible for trend differences. In utero exposure to factors such as tobacco are likely to have remained stable or decreased in pre...

The purpose of this analysis was to evaluate to what extent subsequent malignant neoplasms account for the increasing rates of cancer occurrence among children. Data from the population-based Surveillance, Epidemiology, and End Results program were used to calculate age-standardized annual incidence rates from 1974-1989 for 10 common cancers among children 14 years of age or younger. Mean rates...

Cancer is the most common fatal disease among US children. The fetus has reduced resistance to toxic injury and is especially prone to mutagenic injury because of the high rate of cell division. A fetus can be exposed to environmental toxins through maternal consumption of contaminated water. The objective of this study was to estimate the incidence risk for childhood cancers within each waters...