CE Full-text articles and CE testing at CompendiumVet.com.Send comments/ questions via email compendium@ medimedia.com, fax 800-556-3288, or web CompendiumVet.com. Lipid disorders are common in dogs, with most arising from secondary causes such as endocrine imbalances, cholestatic liver disease, or protein-losing nephropathies.Two primary lipid disorders—idiopathic hyperlipidemia in miniature s...

M any studies have demonstrated that the atherosclerotic process begins in childhood in association with high blood cholesterol levels (1–3). Lipid levels show a strong familial aggregation that has both a genetic and environmental component (4). Monogenic disorders including familial hypercholesterolemia and familial combined hyperlipidemia are expressed in childhood, although adverse diet, po...

Obesity has become a pandemic, with more than a billion people affected worldwide (1). Over the past 30 yr, the frequency of overweight children, defined as a body mass index (BMI) greater than the 85th percentile for age and sex, has tripled (2). More than 30% of children in the United States are overweight or obese (BMI 95th percentile) (3). Data from the International Obesity Task Force indi...

Introduction: The future of any nation depends on how its children's care, According to their likely future health needs of the adult population model for healthy living and wealth has increased. One of the most pressing health diet. This study is done to aimed investigate the factors influencing malnutrition in children in the past for weight loss and weight gain can be seen today.   Methods a...

OBJECTIVE To determine the prevalence of hyperlipidemia among Saudis of both genders in rural and urban communities. METHODS Selected Saudis in the age group of 30-70 years were studied over a 5-year period between 1995 and 2000 in Saudi Arabia. Data were obtained from history, physical examination, and analysis of fasting plasma lipids. The data were analyzed to classify individuals with hyp...

BACKGROUND Familial combined hyperlipidemia (FCHL) is the most commonly inherited hyperlipidemia in men. It constitutes a substantial risk factor for atherosclerosis patients. AIM To delineating the potential mechanism of FCHL by bioinformatics tools. MATERIALS AND METHODS In this study, Protein-Protein Interaction (PPI) network was constructed to identify the potential functional proteins ...

OBJECTIVE Cyclosporin A (CsA) is an immunosuppressant commonly used to prevent organ rejection but is associated with hyperlipidemia and an increased risk of cardiovascular disease. Although studies suggest that CsA-induced hyperlipidemia is mediated by inhibition of low-density lipoprotein receptor (LDLr)-mediated lipoprotein clearance, the data supporting this are inconclusive. We therefore s...

BACKGROUND Many young adults with moderate hyperlipidemia do not meet statin treatment criteria under the new American Heart Association/American College of Cardiology cholesterol guidelines because they focus on 10-year cardiovascular risk. We evaluated the association between years of exposure to hypercholesterolemia in early adulthood and future coronary heart disease (CHD) risk. METHODS A...

Endogenous secretory receptor (esRAGE) for advanced glycation end-product (AGE) acts as decoy for AGEs. The AGE-to-esRAGE ratio was hypothesized to be implicated in diabetic vasculopathy. We investigated an association of esRAGE and methylglyoxal-adducts serum level, as well as AGE-to-esRAGE ratio in subpopulation of diabetic patients with or without concomitant hyperlipidemia and macrovascular...