effective methodologies for efficient preparation of semicarbazones from aldehydes or ketones via milling and the subsequent regeneration of the parent carbonyls by gaseous nitrogen dioxide are described under solid-solid and gas-solid reaction conditions, respectively. these methods are fast, simple and environmentally benign which do not require the use of any auxiliaries such as catalysts or...

With nursing expanding ever upwards and outwards, it should not be surprising that competent and committed auxiliaries will fill the vacuum left behind.

French auxilliaries and clitics have been analysed in the flame of U.C.G. (Unification Categorial Grammar). Concatenation of a functor sign and an adjacent argument sign is the basic operation of the model ; unification allows (a) to verify ff constraints on concatenation are respected ; (b) to produce a flow of information between the functor sign and the argument sign. The rules of the gramma...

Romanian auxiliary verbs exhibit certain peculiar properties that set them aside from other Romance counterparts. It will be suggested that the di erences between Romanian auxiliaries and French and Italian auxiliaries can be accounted for in terms of di erent syntactic structures. While in French and in Italian the auxiliary verb, the non nite one and the complements combine in a at structure,...

Enantiopure sulfoxides are valuable asymmetric starting materials and are important chiral auxiliaries in organic synthesis. Toluene monooxygenases (TMOs) have been shown previously to catalyze regioselective hydroxylation of substituted benzenes and phenols. Here we show that TMOs are also capable of performing enantioselective oxidation reactions of aromatic sulfides. Mutagenesis of position ...

The catalytic highly regio-, diastereo-, and enantioselective synthesis of a small library of spiropyrrolizidineoxindolesvia a four-component 1,3-dipolar cycloaddition reactionof azomethineylides, derived from isatin, with electron-deficient dipolarophilewas described. The process occurs at room temperature in aqueous ethanol as a green solvent and in the presence of a bidendatebis(imi...

The catalytic highly regio-, diastereo-, and enantioselective synthesis of a small library of spiropyrrolizidineoxindolesvia a four-component 1,3-dipolar cycloaddition reactionof azomethineylides, derived from isatin, with electron-deficient dipolarophilewas described. The process occurs at room temperature in aqueous ethanol as a green solvent and in the presence of a bidendatebis(imi...

experimental determination of solubility and ternary phase diagram of chiral compound are of tedious and time consuming tasks, and in many cases, there is not enough experimental data for different enantiomeric compositions to access the experimental ternary phase diagram. using thermodynamic models with predictive capability, having less dependency on experimental data, affords a great advanta...