Cancer remains one of the dreadful disease still today. Chemotherapy, radiotherapy and surgery are effective treatments available for treatment of cancer but have serious side effects. Due to advancement in nanomedicine, several drug carriers have became popular. But chitosan for anticancer drug delivery has became popular due to its easy availability, less cyototoxicity and biodegradability. R...

conclusions: the results showed that silver nanoparticles have an antimicrobial effect against intramacrophage b. abortus 544. results: the well diffusion agar study showed that silver nanoparticles have an antimicrobial effect on b. abortus 544. the mic and mbc of silver nanoparticles against b. abortus 544 were; 6 ppm and 8 ppm, respectively. the silver nanoparticles showed antibacterial effe...

interaction of chrysosporium sps. and aspergillus sps. with aqueous agno3 was investigated for synthesis of silver nanoparticles. biological reduction and extracellular synthesis of silver nanoparticles in 28 hour at 270c and ph 5.6 was done. the nanometallic dispersion was characterized by surface plasmon absorbance measuring at 424 – 530 nm for ag nanoparticles. high resolution transmission e...

Recently, the attention of researchers has been drawn toward the synthesis of chitosan derivatives and their nanoparticles with enhanced antimicrobial activities. In this study, chitosan derivatives with different azides and alkyne groups were synthesized using click chemistry, and these were further transformed into nanoparticles by using the ionotropic gelation method. A series of chitosan de...

objective(s): nanoparticles (nps) are known for their specific accumulation in the inflamed tissues of the colon and thus allow a selective delivery to the site of inflammation with minimum adverse effects. the main objective of this work is to attain mesalamine loaded chitosan nanoparticles as a carrier for oral delivery. methods: in this study, mesalamine loaded chitosan nanoparticles were pr...

Herein, we report natural chitosan end-capped MCM-41 type MSNPs as novel, dual stimuli, responsive nano-vehicles for controlled anticancer drug delivery. The chitosan nanovalves tightly close the pores of the MSNPs to control premature cargo release under physiological conditions but respond to lysozyme and acidic media to release the trapped cargo.

OBJECTIVE To prepare hydroxyethyl chitosan nanoparticles loaded with anti-human death receptor 5 single-chain antibody, and study their characteristics, functions, and mechanisms of action. MATERIALS AND METHODS The anti-human death receptor 5 single-chain antibody was constructed and expressed. Protein-loaded hydroxyethyl chitosan nanoparticles were prepared, and their size, morphology, part...

BACKGROUND AND METHODS A new cyclosporin A-loaded, PEGylated chitosan-modified lipid-based nanoparticle was developed to improve upon the formulation of cyclosporin A. PEGylated chitosan, synthesized in three steps using mild reaction conditions, was used to modify the nanoparticles. Cyclosporin A-loaded, PEGylated chitosan-modified nanoparticles were prepared using an emulsification/solvent ev...

The challenge to achieve appropriate disinfection without forming harmful disinfection byproducts by conventional chemical disinfectants, as well as the growing demand for decentralized or point-of-use water treatment and recycling systems calls for new technologies for efficient disinfection and microbial control. Several natural and engineered nanomaterials have demonstrated strong antimicrob...