Langheld (1) found that sodium hypochlorite reacts with a-amino acids to form chloramino acids, which more or less readily break down to aldehydes or ketones, ammonia, carbonic acid, and sodium chloride. Milroy (2) pointed out that in the case of aromatic or heterocyclic amino acids, such as tyrosine or tryptophane, partial chlorination of the ring takes place in addition to oxidation. Hypochlo...

An efficient, unique, and convenient method for the iodoamidation of olefins with chloramine salts and I(2) in aqueous media is described. This method was applicable to a wide range of olefins, including aromatic, aliphatic, and electron-deficient olefins.

Inhalation of potable water presents a potential route of exposure to opportunistic pathogens and hence warrants significant public health concern. This study used qPCR to detect opportunistic pathogens Legionella spp., L. pneumophila and MAC at multiple points along two potable water distribution pipelines. One used chlorine disinfection and the other chloramine disinfection. Samples were coll...

Human monocytes incubated with phorbol myristate acetate (PMA) or opsonized zymosan particles can chlorinate the beta-amino acid taurine to its monochloramine derivative. Taurine monochloramine can then be quantitated by its ability to oxidize 5-thio-2-nitrobenzoic acid to its disulfide or by its characteristic absorption peak at 252 nm. Stimulated, but not resting, monocytes chlorinated taurin...