We tested the efficacy of preischemic and postischemic systemic treatment with 30,000 units polyethylene glycol-conjugated superoxide dismutase in a reperfusion model of focal cerebral ischemia. Forty-one anesthetized cats underwent 2 hours' occlusion of the left middle cerebral artery and both common carotid arteries followed by 4 hours of reperfusion. Cats were blindly assigned to one of thre...

Abstract Lipoxygenase (LOX, EC1.13.11.12) catalyzes the oxygenation of polyunsaturated fatty acids and further generates oxylipins via enzymatic or non-enzymatic pathways, thus participating in regulation growth development, stress response, other processes. The objective this research was to characterize function evaluate mechanism lipoxygenase gene AfLOX4 ’s role enhancing drought tolerance. ...

Drought is one of the most important abiotic constraints on agricultural productivity, while global warming leads to occurrence more frequent drought events. Cyclocarya paliurus a multiple-function tree species with medicinal value and timber production, but no information available its tolerance. In this hydroponic experiment, variations in leaf anatomical morphology, chloroplast ultrastructur...

OBJECTIVE Resuscitation of hemorrhagic hypotension after traumatic brain injury is challenging. A hemoglobin-based oxygen carrier may offer advantages. The novel therapeutic hemoglobin-based oxygen carrier, polynitroxylated pegylated hemoglobin (PNPH), may represent a neuroprotective hemoglobin-based oxygen carrier for traumatic brain injury resuscitation. HYPOTHESES 1) PNPH is a unique non-n...

The aim of present research was to prepare novel serum stable long circulating polymeric nanoparticles for curcumin with a modification to the well known and novel nanoparticle albumin bound technology. polyethylene glycol-albumin-curcumin nanoparticles were prepared using serum albumin and poly ethylene glycol using desolvation technique. Nanoparticles were characterized for encapsulation effi...

Bioconsequences Section, Unilever Research Port Sunlight Laboratory, Port Sunlight, Wirral, Merseyside L62 4XN, U.K. Polyethylene glycols are an important group of polymers used in the manufacture of explosives, cosmetics and pharmaceuticals. In addition, the polyoxyethylene group is the hydrophilic head group of non-ionic surfactants such as the alcohol ethoxylates used in detergent formulatio...

the effect of grape pomace (vitis vinifera) and in oak leaf (quercus libani) tannins by three runs of in vitro gas production on the organic matter digestibility (omd) and in situ dry matter (dm) and crude protein (cp) disappearance were studied in four sheeps. polyethylene glycol (peg) was used to deactivate the tannins. in vitro gas production was recorded at 2, 4, 6, 8, 12, 48, 72, 96 and 12...

implantable contraceptive is likely to be a promising new option for fertility control, as we have entered the twenty-first century and the world’s population grows by one billion people in a single decade. the main objective of this study was to develop a subdermal implant for levonorgestrol (a synthetic progestin from 19-norandrostanes) using a high molecular weight biodegradable polymer , i....