BACKGROUND The European badger is an important wildlife reservoir of Mycobacterium bovis implicated in the spread of bovine tuberculosis in the United Kingdom and Ireland. Infected badgers are known to shed M. bovis in their urine and faeces, which may contaminate the environment. To aid bovine tuberculosis control efforts novel diagnostic tests for detecting infected and shedding badgers are n...

BACKGROUND Unpasteurised fresh and souring dairy products form an essential component of household diets throughout many rural communities in southern Africa. The presence of milk-borne zoonotic pathogens such as Mycobacterium bovis (M. bovis), the causative agent of bovine tuberculosis and zoonotic tuberculosis in humans, constitute a public health threat, especially in remote areas with poor ...

A sarna bovina é causada pela infestação de ácaros dos gêneros Sarcoptes, Chorioptes, Psoroptes e Demodex, maneira isolada e/ou concomitante. Embora seja encarada como uma condição clínica menor relevância, ainda sim deve ser investigada, principalmente em razão do potencial zoonótico, impacto direto na saúde animais impactos produção animal. principal via transmissão destes bovinos por meio co...

The stated purpose of the second edition of Mycobacterium bovis Infection in Animals and Humans is to provide medical professionals, allied health scientists, research workers, and graduate students with current information on the significance of M. bovis in the control and eradication of tuberculosis in animals and humans. This newest edition deals with topics such as the public health signifi...

Babesia bovis (B. bovis) is a major causative agent of bovine babesiosis, with a considerable worldwide impact. The objective of this study was to evaluate the usefulness of PCR assay and microscopical examination (ME) for detection of B. bovis in naturally infected and apparently healthy water buffaloes and crossbred cattle under field circumstances from Sharkia province of Egypt. A total 34 a...

We screened the levels of antibodies to M. bovis hsp65 and the 180-188 epitope by using ELISA in a cohort of 72 juvenile idiopathic arthritis (JIA) patients and 38 healthy controls. We analysed an association between antibody levels and rheumatoid factor, antinuclear antibodies, human leukocyte antigen B27 and the severity and the duration of the disease. The majority of anti-hsp65 antibodies i...

Mycobacterium bovis (M. bovis) is highly adapted to macrophages and has developed multiple mechanisms to resist intracellular assaults. However, the host cells in turn deploy a multipronged defense mechanism to control bacterial infection. Endoplasmic reticulum (ER) stress-mediated apoptosis is one such primary defense mechanism. However, the role of interferon regulatory factor 3 (IRF3) betwee...

White-tailed deer (Odocoileus virginianus) are reservoirs for Mycobacterium bovis in northeast Michigan, USA. Production of nitric oxide (NO) by activated macrophages is a potent mechanism of mycobacterial killing. The capacity of macrophages to produce NO, however, varies among mammalian species. The objective of this study was to determine if mononuclear cells from white-tailed deer produce n...

BACKGROUND Bovine tuberculosis (bTB) in wildlife species poses a threat to domestic livestock in many situations. Control programs for bTB in livestock depend on testing and slaughtering the positive animals; however, the currently available diagnostic tests often have poor specificity. In our previous study, we developed a specific and sensitive enzyme linked immunosorbent assay (ELISA) for an...

Mycobacterium bovis is the causative agent of bovine tuberculosis (BTB), the pathogen responsible for serious economic impact on the livestock sector. In order to obtain data on isolated M. bovis strains and assist in the control and eradication program for BTB, a cross sectional descriptive molecular epidemiology study in the Brazilian Midwest was conducted. Through spoligotyping and 24-loci M...