introduction wilson’s disease is an autosomal recessive disorder, characterized by a disturbance in copper metabolism that leads to copper overload in different tissues of the body. because of various manifestations of wilson’s disease, physicians should have high index suspicion when patients manifest any type of liver disease, neurologic and psychiatric signs and symptoms. discussion wilson’s...

background: some evidence, not in large study populations, suggests that nonalcoholic fatty liver disease (nafld) and metabolic syndrome (mets) share common interactions. we aimed to determine the prevalence of nafld and mets in a large population registered to kavar cohort study center. we also assessed the role of each component of mets in nafld existence. methods: data were obtained from 341...

conclusions according to the results of this meta-analysis, there was a high risk of nafld in women with pcos. we suggest evaluating patients with pcos regarding nafld. results we finally included seven eligible studies. according to chi-squared test, there was a significant heterogeneity (73.6%) between studies (p = 0.001). nafld prevalence was significantly higher in patients with pcos compar...

conclusions the results confirmed that the total costs for non-alcoholic fatty liver among the iranian adult urban population alone exceeded 1 billion ppp$ per year. these costs can be saved or reduced by effective disease management and early prevention. objectives this study aims to estimate the diagnosis and treatment costs of non-alcoholic fatty liver. patients and methods this cross-sectio...

conclusions twelve weeks of two grams of ginger supplementation showed beneficial effects on some nafld characteristics. further studies are recommended to assess the long-term supplementation effects. results ginger supplementation resulted in a significant reduction in alanine aminotransferase, γ-glutamyl transferase, inflammatory cytokines, as well as the insulin resistance index and hepatic...

introduction the incidence of liver damage due to steroid consumption is increasing due to the omnipresence of the idealized body image and the widespread availability of drugs via the internet. the genetic factors underlying individual susceptibility are not presently known. conclusions this case of pxr haploinsufficiency reveals transcriptional regulatory functions activated in the liver unde...

background: increasing evidence suggests an association between ele­vated serum aminotransferase levels and metabolic disorders (metabolic syndrome, hyperlipemia and diabetes mellitus). however, the significance of relatively low levels of aminotransferases in relation to metabolic disorders has not been fully investigated in the general population. we inves­tigated the association between seru...