Chronic liver disease related to viral hepatitis has emerged as a leading public health problem in the Eastern Mediterranean Region. This paper raises awareness regarding the burden of disease related to viral hepatitis and the need for urgent action to prevent hepatitis B virus and hepatitis C virus transmission. More than 75% of cirrhosis and hepatocellular carcinoma in the Region is attribut...

background and aims: hepatitis d virus (hdv) can infect human population either as a superinfection or concurrent hepatitis b virus (hbv) infection. it is expected that presence of hdv infection is more prevalent in endemic hbv areas. overall 5% of iranian general populations are chronic hbv carriers. the aim of this study was to determine the seroprevalence of hdv and its clinical impact in a ...

A 37-year-man with chronic hepatitis B was diagnosed as having antimicrosomal antibodies and subclinical hypothyroidism. The association of autoimmune manifestations with hepatitis B has been less frequently reported than with hepatitis C virus. It is discussed whether this patient illustrates a case of spontaneous development of antimicrosomal antibodies, only casually associated with the pres...

Hepatitis B virus co-infection with C and/or D is known to result in a more deleterious disease than chronic HBV mono-infection, resulting faster progression cirrhosis and hepatocellular carcinoma. This study aimed at determining the serological prevalence of infections among carriers frequency e Antigen tertiary hospital South-East, Nigeria. cross-sectional involving 72 consenting participants...

Resulting directly from the discovery of virus-related antigens, rapid progress has marked the last decade of viral hepatitis research. The hepatitis B virion has been tentatively identified as a DNA virus with an endogenous DNA polymerase, and new serological markers for type B hepatitis have been discovered. Hepatitis A antigen has been identified on a virus-like particle thought to be the he...

Background and aims: The frequency of chronic hepatitis B virus infection varies totally in different part of the world but it could be categorized as high, intermediate and low endimicity. In this regard, development of safe and effective vaccines against infectious diseases especially hepatitis B virus that are still required for emerging new pathogens, re-emerging old pathog...

BACKGROUND Since the introduction of Highly Active Anti-Retroviral Therapy and the dramatic improvement in the prognosis of individuals with Human Immunodeficiency Virus, liver disease due to chronic viral hepatitis has become as important cause of morbidity and mortality in co-infected individuals. The objective of the study was to determine the Sero-prevalence of Hepatitis B Virus, Hepatitis ...

Hepatitis B is a global acute and chronic life-threatening liver infection caused by the hepatitis virus. During cadaveric dissection, clinical rotations, autopsy posting, medical students get exposed to patients’ blood body fluids, which increases risk of infection. can be prevented vaccines that are safe, easily available, effective, however many still unvaccinated. This results in need for a...

context hepatitis b and hepatitis c (hbv and hcv) infections are both major causes of hepatocellular carcinoma (hcc). however, hcc caused by each of these two viruses has unique characteristics that should be studied independently to that of another one. while hbv- and hcv-related hccs share similar host and environmental risk factors such as male gender, age above 50 years old, family history ...

Hepatitis B virus (HBV) is an enveloped virus with a small (3.2-kb) partially double-stranded DNA genome that causes acute and chronic infections. The impact of these infections on public health worldwide is enormous, with an estimated prevalence of 2 billion acute infections and 360 million chronic infections globally. This review focuses on chronic hepatitis B and the molecular assays used in...