Psoriasis is a chronic, immune-mediated inflammatory skin disorder that affects 2-3% of the population worldwide. Current therapies, including biologic agents, often have adverse effects and incomplete efficacy. Recent studies suggest PI3K/AKT/FOXO signalling cascade interleukin-1 β play crucial role in pathogenesis psoriasis. Hyperbaric oxygen therapy, safe well-tolerated procedure, has been s...

Asthma is a chronic heterogeneous inflammatory disorder/syndrome of the airways that affects more than 300 Million people worldwide. often starts in childhood (Allergic phenotype).Co morbidities trigger asthma exacerbations. It’s difficult to diagnose young children. Objective tests lung function aid diagnosis children > six years age. has phenotypes and endotypes. Biomarkers Ex. Fractional ...

Lichen planus (LP) is a chronic lichenoid inflammatory disorder of the skin, mucosa and appendages. LP classically characterized by presence rich infiltration T cells, which migrate in upper part dermis, arranged band-like pattern. Different sub types disease have been so far described. Albeit clinically well defined, still represents therapeutic enigma. Especially with regard to mucosal or sca...

background: parents of children with developmental problems are always bearing a load of stress. the aim of this study is to compare the stress in mothers of children with different disabilities to each other, considering their demographic background. materials and methods: this was a cross-sectional study conducted in isfahan, iran during 2012 on 285 mothers of 6-12 years old children with chr...

screening is one of the ways to combat tuberculosis (tb) and should be mostly concentrated on groups showing some symptoms of the disease. tuberculosis can be transferred from person to person in laboratories, prisons and psychiatry hospitals. the purpose of this study was to survey pulmonary tb in patients with schizophrenia in rasht.in this descriptive-cross sectional, two hundred fifty seven...

INTRODUCTION Tumefactive fibroinflammatory lesion is an idiopathic fibrosclerosing disorder occurring in the head and neck region. It is one of a broad spectrum of entities named inflammatory pseudotumors and, as the name suggests, it mimics a lot of diseases such as malignancies or infections. Combined with its rarity, tumefactive fibroinflammatory lesion can be a tremendous diagnostic challen...

Background: We now know that depression is associated with a chronic, low-grade inflammatory response and activation of cell-mediated immunity, as well as activation of the compensatory anti-inflammatory reflex system. It is similarly accompanied by increased oxidative and nitrosative stress (O&NS), which contribute to neuroprogression in the disorder. The obvious question this poses is ‘what i...

BACKGROUND We now know that depression is associated with a chronic, low-grade inflammatory response and activation of cell-mediated immunity, as well as activation of the compensatory anti-inflammatory reflex system. It is similarly accompanied by increased oxidative and nitrosative stress (O&NS), which contribute to neuroprogression in the disorder. The obvious question this poses is 'what is...

Inflammatory bowel disease is a group of chronic medical conditions comprising Crohn's disease and ulcerative colitis that involves increased frequency of mental disorders. The most common psychiatric disorders in inflammatory bowel disease are depression and anxiety, however, some epidemiologic and biological evidence suggest that other disorders like bipolar disorder occur more often. Biologi...

KIMURA'S DISEASE is a rare condition and manifests as solitary or multiple subcutaneous nodules in the head and neck region, with eosinophilia and adenopathy. It is a benign chronic inflammatory disorder of unknown etiology. Histologically the lesions are characterized by hyperplastic lymphoid tissue, an inflammatory infiltrate rich in eosinophils and a proliferation of postcapillary venules. H...