BACKGROUND Hepatitis C virus (HCV) infection can predispose to the development of insulin resistance before diabetes occurs. Such a potential link is particularly cogent in light of recent data indicate that diabetes may be associated with increased hepatic fibrosis progression in patients with chronic HCV infection. The aim of the study is to determine the prevalence of insulin resistance in n...

conclusions several adverse effects are associated to anti-hcv drugs, hence appropriate skin care management and follow-up are very important. a careful anamnesis before the initiation of triple therapy is necessary to identify previous dermatological diseases that could increase skin adverse effects incidence. case presentation we report a case of a patient who discontinued telaprevir because ...

The aim of the review is to highlight main factors affecting development liver fibrosis and possible mechanisms damage in patients who have experienced COVID-19. A search was carried out using keywords Scopus, Web Science, PubMed databases literary sources last three years on associated with fibrogenesis novel coronavirus infection. presents COVID-19: direct effects hepatocytes cholangiocytes, ...

The immuno-pathogenic mechanisms of chronic hepatitis C virus (HCV) infection remain to be elucidated and pose a major hurdle in treating or preventing chronic HCV-induced advanced liver diseases such as cirrhosis. Macrophages are a major component of the inflammatory milieu in chronic HCV-induced liver disease, and are generally derived from circulating inflammatory monocytes; however very lit...

Chronic liver diseases represent a global health problem due to their high prevalence worldwide and the limited available curative treatment options. They can result from various causes, both infectious and noninfectious diseases. The application of nanoparticle (NP) systems has emerged as a rapidly evolving area of interest for the safe delivery of various drugs and nucleic acids for chronic l...