نتایج جستجو برای: chronic mucocutaneous

تعداد نتایج: 499713  

2012
Anna R Huppler Shrinivas Bishu Sarah L Gaffen

IL-17 and related cytokines are direct and indirect targets of selective immunosuppressive agents for the treatment of autoimmune diseases and other diseases of pathologic inflammation. Insights into the potential adverse effects of IL-17 blockade can be drawn from the experience of patients with deficiencies in the IL-17 pathway. A unifying theme of susceptibility to mucocutaneous candidiasis ...

Journal: :The British journal of dermatology 2001
M Bilic D F Mutasim

Patients with Behçet's disease may develop multiple mucocutaneous manifestations, several of which are mediated by neutrophils. These include aphthous ulcers, pseudofolliculitis, acneform lesions, and pathergy. We report another neutrophil-mediated disorder, neutrophilic eccrine hidradenitis (NEH), in a patient with Behçet's disease. NEH should be added to the list of mucocutaneous lesions that...

Journal: :Cutis 2011
Payman Kosari Kristen M Kelly

Laugier-Hunziker syndrome is a rare mucocutaneous pigmentary disorder. It is considered benign, but other mucocutaneous pigmentation disorders are in the differential diagnosis and should be ruled out. This report describes a woman with pigmentation of the labial mucosa of the lower lip who was successfully treated with a Q-switched 532-nm laser.

ژورنال: مجله دندانپزشکی 2019

Background and Aims: Lichen planus is a chronic inflammatory mucocutaneous disease with unknown etiology. One of the most common manifestations of patients with oral lichen planus is gingival involvement in the form of generalized erythematous areas. The aim of this study was to review the articles evaluating the role of plaque control on the gingival manifestations of oral lichen planus. Mate...

2015
Saifuddin Sheikh Ateeq Ahmad Shoukath M Ali Mahesh Paithankar Hanmant Barkate Ranjan C Raval Kalpesh Shah Bhavik A Bhavsar Manish Sharma Imran Ahmad

Objectives: A novel topical formulation of lipid based amphotericin B (0.1% amphotericin B Gel) was developed to assess the safety, tolerability and efficacy in adult patients with cutaneous and/or mucocutaneous fungal infection. Methods: Amphotericin B gel was formulated using lipids. In vitro release assay of amphotericin B was measured using paddle apparatus maintained at 37.0° ± 0.5°C. The ...

Journal: :Otolaryngology–Head and Neck Surgery 2005

Journal: :Trends in immunology 2016
Sakeen W Kashem Daniel H Kaplan

Candida albicans is a dimorphic commensal fungus that colonizes healthy human skin, mucosa, and the reproductive tract. C. albicans is also a predominantly opportunistic fungal pathogen, leading to disease manifestations such as disseminated candidiasis and chronic mucocutaneous candidiasis (CMC). The differing host susceptibilities for the sites of C. albicans infection have revealed tissue co...

2013
Beáta Soltész Beáta Tóth Nadejda Shabashova Anastasia Bondarenko Satoshi Okada Sophie Cypowyj Avinash Abhyankar Gabriella Csorba Szilvia Taskó Adrien Katalin Sarkadi Leonóra Méhes Pavel Rozsíval David Neumann Liudmyla Chernyshova Zsolt Tulassay Anne Puel Jean-Laurent Casanova Anna Sediva Jiri Litzman László Maródi

BACKGROUND Chronic mucocutaneous candidiasis disease (CMCD) may result from various inborn errors of interleukin (IL)-17-mediated immunity. Twelve of the 13 causal mutations described to date affect the coiled-coil domain (CCD) of STAT1. Several mutations, including R274W in particular, are recurrent, but the underlying mechanism is unclear. OBJECTIVE To investigate and describe nine patients...

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