To determine how the presence of generalised airflow limitation due to chronic obstructive lung disease affects the recognition of simulated upper airway obstruction, a study was carried out in 12 patients (mean (SD) age 57 (7) years) with chronic obstructive lung disease (FEV1% predicted 53 (22), range 21-70) and 12 matched control subjects. Patients and control subjects performed maximal insp...

materials and methods weighted logistic regression models were used for the analysis of 1,248 cases and 39,995 controls from the 2005 california health interview survey (chis). results the prevalence of spd was 10% in cases and 4% in controls, respectively. the percentages of past and current smoking were higher in cases than controls (50% vs. 24% and 27% vs. 15%, respectively). after adjusting...

the purpose of this study was to examine the effect of intravenous magnesium sulfate on patients with copd exacerbation requiring hospitalization. in this randomized clinical trial 30 patients with copd exacerbation were studied. patients were randomly assigned to group a (case) who concurrent with standard therapy received 2g magnesium sulfate in normal saline infused in 20 minutes on days one...

background: postoperative cognitive dysfunction (pocd) has been an important complication of cardiac surgery over the years. neurocognitive dysfunction can affect quality of life and lead to social, functional, emotional, and financial problems in the patient’s life. to reduce pocd, we sought to identify the association between cognitive dysfunction and perioperative factors in patients undergo...

background: given the importance of the chronic obstructive pulmonary disease (copd) and role of different factors in self-care behaviors of copd patients, this study was conducted to determine the effect of self-efficacy program on self-care behaviors of copd patients. materials and methods: in this semi-experimental study, 62 copd patients were recruited in which 31 subjects were in control g...

It is not an uncommon situation to encounter a patient for anaesthesia with multiple co-morbidities. Here we report successful anaesthetic management of Hypertrophic Obstructive Cardiomyopathy, Stage IV Chronic Kidney Disease, Lung Infection, immunosuppressed, posted minimally invasive video assisted thoracoscopy requiring one lung ventilation. Intraoperative hemodynamic stability was maintaine...

Until the 1960's there was great confusion, both within and between countries, on the meaning of diagnostic terms such as emphysema, asthma, and chronic brochitis. Proposals made by a group of British doctors in 1959 gradually received widespread acceptance but in recent years some new problems have developed. These include difficulties in the definition of airflow obstruction, recognition that...

BACKGROUND Domiciliary assisted ventilation, using negative or positive pressure devices, is an effective treatment for respiratory failure due to chest wall deformity and neuromuscular disease. Negative pressure ventilators have been used with some success in patients with chronic obstructive lung disease in hospital, but attempts to continue treatment at home have been disappointing. This stu...

  Background: Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease, which reduces the lung function and causes respiratory symptoms over time, and it is primarily associated with shortness of breath, cough and sputum production. Roflumilast, which is a long-acting selective inhibitor, reduces the anti-inflammatory effect of the main symptoms of COPD. The aim of ...

The composition of the lung microbiome contributes to both health and disease, including obstructive lung disease. Because it has been estimated that over 70% of the bacterial species on body surfaces cannot be cultured by currently available techniques, traditional culture techniques are no longer the gold standard for microbial investigation. Advanced techniques that identify bacterial sequen...