Chronic rhinosinusitis (CRS) is a heterogeneous disease process primarily considered to be of nasal origin. Highlighted in this case, CRS may result from an odontogenic infection. An 82-year-old man presented with 6-month history malodor and purulent drainage. He endorsed recurrent frontal headaches, anosmia, dysgeusia, but denied odontalgia. had been treated 2 courses oral antibiotics without ...

1 Craven DE, Chroneou A, Zias N, et al. Ventilator-associated tracheobronchitis: the impact of targeted antibiotic therapy on patient outcomes. Chest 2009; 135:521–528 2 Paju S, Scannapieco FA. Oral biofilms, perodontitis, and pulmonary infections. Oral Dis 2007; 13:508–512 3 Prince AA, Steiger JD, Khalid AN, et al. Prevalence of biofilms-forming bacteria in chronic rhinosinusitis. Am J Rhinol ...

Background It is believed that immunosuppression is the sole cause for the occurrence of rhinosinusitis in hematopoietic stem cell transplant (HSCT). There is a high incidence of sinusitis in recipient’s patients, especially those with Chronic Graft Versus Host disease (GVHD). Histopathological abnormalities were described in recipient’s sinus mucosa comparing to the immunocompetents patients. ...

BACKGROUND The united allergic airway is a theory that connects allergic rhinitis (AR), chronic rhinosinusitis, and asthma, in which seemingly disparate diseases, instead of being thought of separately, are instead viewed as arising from a common atopic entity. OBJECTIVE This article describes patients with such diseases; explores ideas suggesting a unified pathogenesis; elucidates the variou...

Chronic rhinosinusitis with nasal polyps is a common disease with still unclear pathophysiologic mechanisms. The airway epithelial barrier has been shown to be involved in different chronic disorders, including rhinitis, nasal polyposis and asthma. High mobility group box 1 (HMGB1), a primarily nuclear protein, is involved in the induction of airway inflammation in patients with chronic rhinosi...

Patients with HIV/AIDS can present with multiple types of fungal rhinosinusitis, fungal balls, granulomatous invasive fungal rhinosinusitis, acute or chronic invasive fungal rhinosinusitis, or allergic fungal rhinosinusitis (AFRS). Given the variable spectrum of immune status and susceptibility to severe infection from opportunistic pathogens it is extremely important that clinicians distinguis...

OBJECTIVES/HYPOTHESIS Associations between olfactory function to quality-of-life (QOL) and disease severity in patients with rhinosinusitis is poorly understood. We sought to evaluate and compare olfactory function between subgroups of patients with rhinosinusitis using the Brief Smell Identification Test (B-SIT). STUDY DESIGN Cross-sectional evaluation of a multicenter cohort. METHODS Pati...

OBJECTIVE To systematically review the evidence on allergic rhinitis as a predictor for a prolonged or chronic course in adult patients with acute rhinosinusitis. DATA SOURCES Pubmed, EMBASE, and the Cochrane library. REVIEW METHODS A systematic literature search was performed on March 15, 2013. During screening of title and abstract, 3 authors independently selected studies on allergic rhi...