Introduction: Chronic osteomyelitis and infected non-union are relatively rare conditions in pediatric patients and are more frequently observed in the developing countries. Although relatively rare, they are challenging medical and surgical issues. The current study aimed to present a novel surgical technique used to manage three patients with chronic osteomyelitis of long bones. Case Presenta...

DISCLOSURE There are no conflicts of interest to be declared. No financial support was obtained from any party for the study ABSTRACT Background: Chronic osteomyelitis is a challenging condition both to the clinician and the patient. Despite the advances that have been made in the areas of antibiotic management and operative treatment, the condition is still associated with high incidence of re...

Introduction We report a severe case of chronic non-bacterial osteomyelitis (CNO) associated with total myeloperoxidase (MPO) deficiency. Chronic non-bacterial osteomyelitis (CNO) is often considered an autoinflammatory disease. In pediatric literature CNO is often referred to as chronic recurrent multifocal ostemyelitis (CRMO). CNO is occasionally associated with extremely rare monogenic disea...

We present a 10-year old boy with recurrent swelling of the right mandibular region. Based on the diagnosis of chronic recurrent parotitis, he received only supportive treatment. Because of frequent relapses, the diagnosis was reconsidered. Magnetic resonance imaging, scintigraphy and biopsy were compatible with chronic osteomyelitis. This lead to a diagnosis of mandibular primary chronic osteo...

Introduction Chronic nonbacterial osteomyelitis (CNO) is an autoinflammatory bone disorder mostly affecting children and adolescents. Chronic recurrent multifocal osteomyelitis (CRMO) is the most severe form of CNO. It is characterized by recurring episodes of bone inflammation that can last for years and may cause chronic pain, pathological fractures, and disability. Despite recent advances in...

It is suspected that the pathogenesis of autoimmune pancreatitis (AIP) is still unknown, although it has become recognized as a distinct entity worldwide. The characteristic findings in most cases of AIP can be summarized as follows: (i) mild abdominal symptoms, usually without acute attacks of pancreatitis; (ii) occasional existence of obstructive jaundice; (iii) increased levels of serum gamm...

We present two cases of spontaneous dislocation of the hip joint due to chronic osteomyelitis of the upper femur. Spontaneous hip dislocations occur in certain pathological conditions such as poliomyelitis (Ingram, 1980), cerebral palsy (Howard et al., 1985), osteomyelitis and neurofibromatosis.

Osteomyelitis resulting from a mold infection often presents as a chronic and indolent disease process. Described here for the first time is a case of osteomyelitis of the foot caused by the mold Pseudallescheria fusoidea, which resulted from traumatic implantation after an injury sustained 3 years earlier.

Primary sclerosing cholangitis, a chronic progressive cholestatic liver disease, is the most serious hepatobiliary complication of ulcerative colitis (UC). The authors present the case of a severe and intractable form of UC associated with primary sclerosing cholangitis, in which the diagnosis of this hepatobiliary complication was made during the postmortem examination. A 19-year-old man, with...

In recent years, autoimmune pancreatitis has been established as a special type of chronic pancreatitis. It is characterized by its histopathological and immunological features. The morphological hallmarks are periductal infiltration by lymphocytes and plasma cells and granulocytic epithelial lesions with consequent destruction of the duct epithelium and venulitis. Autoimmune pancreatitis has t...