Objective: To compare the efficacy of autologous serum with Antihistamine therapy in treating chronic urticaria.
 Study Design: Quasi-experimental study.
 Place and Duration Study: Dermatology Department, Pak Emirate Military Hospital, Rawalpindi Pakistan, from Jul 2018 to Jan 2019.
 Methodology: One hundred four patients urticaria (≥3 times/ week for ≥6 weeks) ages ranging 16 70...

Sir, Although the literature on urticaria is vast, only few studies are available on acute urticaria (AU), and this is especially true for the prognosis in children (1, 2). The first study of AU in young children was not published until 1990 (3), and a second on hospitalized 1–3-yearolds almost a decade later (4). These studies suggested that between 20% and 30% of young children with AU are at...

Urticaria is a kind of skin rash that sometimes caused by allergic reactions. Acute viral infection, stress, pressure, exercise and sunlight are some other causes of urticaria. However, chronic urticaria and angioedema could be either idiopathic or caused by autoimmune reaction. They last more than six weeks and could even persist for a very long time. It is thought that the level of C-reactive...

Delayed pressure urticaria (DPU) is characterized by deep dermal wheals that appear in response to a local continuous pressure. Although it has been reported to complicate as many as 40% of cases of Caucasian patients with chronic urticaria, no definitive cases of Asian/Japanese patients have been reported in English literature. Here, we identified 17 cases of DPU, among 540 Japanese patients w...

Omalizumab is a recombinant humanized monoclonal antibody that blocks the high-affinity Fc receptor of IgE. Omalizumab has been approved for the treatment of moderate to severe asthma; however, there is currently more and more data showing promising results in the management also of chronic urticaria. We present a case series of 19 patients with chronic urticaria treated in a university departm...

Chronic urticaria (CU) in children often is caused by physical triggers. It also can be associated with autoimmune disease, especially thyroid autoimmunity. Functional autoantibodies against FcepsilonRIalpha have been reported in children with CU but have not been studied in a systematic fashion. The autologous serum skin test has been proposed as a surrogate test to define the presence of thes...