Brucella abortus cyclic glucan synthase (Cgs) is a 316-kDa (2,831-amino-acid) integral inner membrane protein that is responsible for the synthesis of cyclic beta-1,2-glucan by a novel mechanism in which the enzyme itself acts as a protein intermediate. B. abortus Cgs uses UDP-glucose as a sugar donor and has the three enzymatic activities necessary for synthesis of the cyclic polysaccharide (i...

Adenosine is a known inhibitor of respiratory output during early life. In this study we investigated the developmental changes in adenosine A2A-receptor activation on respiratory timing, as well as the relationship between adenosine and GABA. The specific adenosine A2A-receptor agonist CGS-21680 (CGS) or vehicle control was injected into the fourth ventricle of 14-day (n = 9), 21-day (n = 9), ...

Actin is involved in endocytosis in organisms ranging from yeast to mammals. In activated Xenopus eggs, exocytosing cortical granules (CGs) are surrounded by actin "coats," which compress the exocytosing compartments, resulting in compensatory endocytosis. Here, we examined the roles of two myosins in actin coat compression. Myosin-2 is recruited to exocytosing CGs late in coat compression. Inh...

The nuclear envelope (NE) presents a physical boundary between the cytoplasm and the nucleoplasm, sandwiched in between two highly active systems inside the cell: cytoskeleton and chromatin. NE defines the shape and size of the cell nucleus, which increases during the cell cycle, accommodating for chromosome decondensation followed by genome duplication. In this work, we study nuclear shape flu...

We study Sowa’s conceptual graphs (CGs) with both existential and universal quantifiers. We explore in detail the existential fragment. We extend and modify Sowa’s original graph derivation system with new rules and prove the soundness and completeness theorem with respect to Sowa’s standard interpretation of CGs into first order logic (FOL). The proof is obtained by reducing the graph derivati...

Makassar City as the capital city of South Sulawesi province has potential and opportunity to develop its fishery industry become center largest in Eastern Indonesia. One fishing ports is a Paotere fish landing station. The station northern part located on Jl. Sabutung I No.3, Kelurahan Gusung, Ujung Tanah District, port that many activities related auction needs, such auction, unloading, ship ...

We explored the mediation effect of caregiver self-efficacy on the influences of behavioral and psychological symptoms (BPSD) of dementia care recipients (CRs) or family caregivers' (CGs) social supports (informational, tangible and affectionate support and positive social interaction) on CGs' mental health. We interviewed 196 CGs, using a battery of measures including demographic data of the d...

In this paper, we propose a novel approach called Wikipedia-based Collapsed Gibbs sampling (Wikipedia-based CGS) to improve the efficiency of the collapsed Gibbs sampling(CGS), which has been widely used in latent Dirichlet Allocation (LDA) model. Conventional CGS method views each word in the documents as an equal status for the topic modeling. Moreover, sampling all the words in the documents...

The Conjugate Gradient Squared (CGS) is a well-known and widely used iterative method for solving non-symmetric linear systems of equations. In practice the method converges fast, often twice as fast as the Bi-Conjugate Gradient (Bi-CG) method. However, during the iteration large residual norms may appear, which may lead to inaccurate approximate solutions or may even deteriorate the convergenc...

Computer-Interpretable Guidelines (CIGs) are representations of Clinical Guidelines (CGs) in computer interpretable languages. CIGs have been pointed as an alternative to deal with the various limitations of paper based CGs to support healthcare activities. Although the improvements offered by existing CIG languages, the complexity of the medical domain requires advanced features in order to re...