Current palliative pharmacotherapy of Alzheimer’s disease based on the cholinergic hypothesisled to the development of four cholinesterase inhibitors. These compounds can bring prolongationof the symptom-free period in some patients. This is the frst report directly comparing donepeziland rivastigmine plasma and brain levels in <span class="font...

In response to widespread dissatisfaction with its public schools, California has implemented a number of educational reforms over the past decade. Perhaps the most dramatic, and certainly the most costly, was the passage of the class size reduction (CSR) law in the summer of 1996. This legislation aimed to reduce average class size by roughly one-third, from 30 students to 20, in grades kinder...

Social science research suggests that reducing class size has its largest effects on the achievement of minority and inner-city children during the first year of formal schooling.' Despite scholarly disagreements about the implications of specific studies on class size, economists generally agree that targeted class-size policies rest on stronger evidence than untargeted policies. For example, ...

Size-selective mortality inevitably leads to a decrease in population density and exerts a direct negative effect on targeted size classes. But density and population size structure are also shaped by food-dependent processes, such as individual growth, maturation, and reproduction. Mortality relaxes competition and thereby alters the dynamic interplay among these processes. As shown by the rec...

Numerous studies have investigated the impact of class size on student outcomes. This analysis contributes to this discussion by isolating the impact of class size on student outcomes in higher education by utilizing a natural experiment at a selective institution which enables the estimation of class size effects conditional on the total number of students taught by a faculty member. We find t...

When students select a university, one of the important parameters is the average class size. This average is usually estimated as an arithmetic average of all the class sizes. However, it has been recently shown that to more adequately describe students’ perception of a class size, it makes more sense to average not over classes, but over all students – which leads to a different characteristi...