Light scattering in biological tissues can be reduced by using optical clearing agents. Various physical methods in conjunction with agents have been studied to enhance the optical clearing efficacy of skin for diagnostic and therapeutic applications. In this study, we propose a new physical method to enhance the optical clearing potential of topically applied glycerol. A microneedle roller is ...

Tissue optical clearing technique shows a great potential for neural imaging with high resolution, especially for connectomics in brain. The passive clarity technique (PACT) is a relative simple clearing method based on incubation, which has a great advantage on tissue transparency, fluorescence preservation and immunostaining compatibility for imaging tissue blocks. However, this method suffer...

We study the limiting distribution of the degree of a given node in a scaled attachment random recursive tree, a generalized random recursive tree, which is introduced by Devroye et. al (2011). In a scaled attachment random recursive tree, every node $i$ is attached to the node labeled $lfloor iX_i floor$ where $X_0$, $ldots$ , $X_n$ is a sequence of i.i.d. random variables, with support in [0,...

In this article, we discuss the optical immersion method based on refractive index matching of scatterers (e.g., collagen, elastin fibers, cells and cell compartments) and the ground material (interstitial fluid and/or cytoplasm) of tissue and blood under the action of exogenous optical clearing agents. We analyze the optical clearing of fibrous and cell-structured tissues and blood from the po...

A possible relationship may exist between the concentration of heparin-activated plasma clearing factor and alterations in lipid metabolism associated with advancing age, atherosclerosis, and other diseases. To test this hypothesis, 121 men were evaluated in the development and application of a standardized in vitro method for the determination of clearing factor response to minimal heparin sti...

We study algorithms for combinatorial market design problems, where a set of heterogeneous and indivisible objects are priced and sold to potential buyers subject to equilibrium constraints. Extending the CWE notion introduced by Feldman et al. [STOC 2013], we introduce the concept of a Market-Clearing Combinatorial Walrasian Equilibium (MC-CWE) as a natural relaxation of the classical Walrasia...

SUMMARY A small remnant of native forest and scrub located in the upper East Branch of the Tokomairiro River is described and assessed for ecological significance. Vegetation grades from pasture on rolling ridges through bracken, Himalayan honeysuckle, gorse and broom scrub on upper gully slopes, to a mosaic of forest types characterised by kanuka, common broadleaved species, or narrow-leaved l...