The fruit of Pyrus ussuriensis is typically climacteric. During ripening, the fruits produce a large amount of ethylene, and their firmness drops rapidly. Although the molecular basis of climacteric fruit ripening has been studied in depth, some aspects remain unclear. Here, we compared the transcriptomes of pre- and post-climacteric fruits of Chinese pear (P. ussuriensis c.v. Nanguo) using RNA...

OBJECTIVE To assess the efficacy and tolerability of intravaginal rings (IVRs) delivering estradiol. DESIGN This was a dose-escalating, continuous-dosing, pilot study. METHODS Sixteen women post surgical menopause were recruited at a hospital-based menopause clinic. Over 20 weeks, each patient had IVR devices releasing 50, 75, 100, 150 and 200 mug/day of estradiol inserted consecutively at ...

Induced cells of Rhodococcus rhodochrous DAP 96253, when placed in the proximity of climacteric fruit (peaches, bananas, avocados) delay the ripening of the fruit. Examination of the delayed ripening shows that the induced cells possess multiple mechanisms that have the potential to impact the Yang Cycle in climacteric plants and processes such as volatile flavor and fragrance compounds related...

OBJECTIVES In the present study, therapeutic effects of the Cimicifuga racemosa preparation CR BNO 1055 (Klimadynon/Menofem) on climacteric complaints, bone metabolism and endometrium will be compared with those of conjugated estrogens (CE) and placebo. The question whether CR BNO 1055 contains substances with selective estrogen receptor modulator (SERM) activity will be investigated. METHODS...

Background: Some women get through their monthly periods easily with few or no concerns. However, other experience a host of physical and/or emotional symptoms just before and during menstruation (heavy bleeding missed to unmanageable mood swings). These premenstrual syndrome (PMS) usually start be problematic in the adolescent years decline climacteric. Symptoms have devastating effect which s...

Changes in the metabolic hormonal balance during the climacteric and menopause, especially surgically induced menopause, increase the risk of acute cerebrocardiovascular complications. This major risk may be linked to changes in blood pressure. In this study we performed twenty-four ambulatory blood pressure monitoring in climacteric (C), menopausal (PM), and surgically induced menopausal women...

Lumbar spine and proximal femoral bone densities of Caucasian women, aged 35-45, were measured by dual photon densitometry model DPX. The measurement sites were assessed at the lumbar spine (vertebrae L2 to L4) and at the proximal femur (trochanter, femoral neck and Ward's triangle). After exclusion of women with climacteric symptoms, sterilized patients or those with menopausal concentrations ...

woman seeking relief from menopausal.svmptoms is common in Westesn society. Many women, however, suffer in silence or take the plunge towards synthetic hormone replacement therapy (HRT). Whilst the untoward symptoms of the female climacteric (change of life) are troublesome, the postmenopausal onslaught of degenerative diseases is the real health problem that faces the mature female. New inform...