Globally, lung disease is one of the contributors to increase in inpatients and use health facilities hospitals. This literature review aims identify effectiveness implementing integrated clinical pathways disease. Methods: The design this research a review. Search articles using Pubmed, Ebsco, Cochrane Library, Proquest databases. Structured questions PICO method, search keywords based on data...

BACKGROUND The clinical pathway is a tool that operationalizes best evidence recommendations and clinical practice guidelines in an accessible format for 'point of care' management by multidisciplinary health teams in hospital settings. While high-quality, expert-developed clinical pathways have many potential benefits, their impact has been limited by variable implementation strategies and sub...

Clinical pathways (CPWs) are a common component in the quest to improve the quality of health. CPWs are used to reduce variation, improve quality of care, and maximize the outcomes for specific groups of patients. An ongoing challenge is the operationalization of a definition of CPW in healthcare. This may be attributable to both the differences in definition and a lack of conceptualization in ...

KRAS mutations are mutually exclusive with other activating on EGFR pathway. Detection of associated tumorigenesis, predicates the lack same pathway and shows that application targeted therapy approaches which target proteins in EGFR-MAPK ineffective. In this study, frequency colorectal cancer relationship between mutation status clinical features were assessed. detected 47,7% cases included ou...

Objective(s): Arachidonic Acid/5-lipoxygenase (AA/5-LOX) pathway connects lipid metabolism and proinflammatory cytokine, which are both related to the development and progression of nonalcoholic fatty liver disease (NAFLD). Therefore, the present study was designed to investigate the role of AA/5-LOX pathway in progression of NAFLD, and the effect of zileuton, an inhibitor of 5-LOX, in this mod...