Introduction. Laparoscopic and robot-assisted laparoscopic surgery are widely performed in urology field, so Hem-o-Lok clips are thus extensively used in the laparoscopic procedures. We describe the first case of Hem-o-Lok clip which migrated into the neobladder with calculus formation 26 months after laparoscopic orthotopic neobladder cystectomy, which causes symptoms of gross hematuria and fr...

PURPOSE To evaluate the efficacy and stability of the wrap-clipping methods as a reconstructive strategy in the treatment of unclippable cerebral aneurysms. MATERIALS AND METHODS Twenty four patients who had undergone wrap-clipping microsurgery were retrospectively reviewed. Type and morphology of the treated aneurysm, utilized technique for wrap-clip procedure, and clinical outcome with angi...

CLIP-seq experiments are currently the most important means for determining the binding sites of RNA binding proteins on a genome-wide level. The computational analysis can be divided into three steps. In the first pre-processing stage, raw reads have to be trimmed and mapped to the genome. This step has to be specifically adapted for each CLIP-seq protocol. The next step is peak calling, which...

Cytoplasmic linker protein (CLIP)-170 is a microtubule (MT) plus-end-tracking protein that regulates MT dynamics and links MT plus ends to different intracellular structures. We have shown previously that intramolecular association between the N and C termini results in autoinhibition of CLIP-170, thus altering its binding to MTs and the dynactin subunit p150(Glued) (J. Cell Biol. 2004: 166, 10...

W hen our human ancestors began to migrate from the African savannahs across the Alps into Northern Europe and Asia between 200,000 and 60,000 years ago, they encountered a colder climate, different food sources and new predators. Inevitably, evolution began to work on those wandering tribes: their skin became lighter, their metabolism adapted to new food sources, and their immune system had to...

United colours: Some may fear immigration as a novel phenomenon endangering established cultural and ethnic units, but research has shown that humans have always migrated and mixed. A recent global study suggests that more than 94% of individuals have significantly mixed ancestry. The picture shows a scene from the Cowley Road Carnival at Oxford, UK. (Photo: Michael Gross.) Migration is one of ...

Fencing in wildlife from human intrusion is becoming increasingly attractive in some regions (see page R465) but there are also worries that the effects of these fences and other human activity are having a major impact on the movement of the world's most spectacular migrating species. All the world's large-scale terrestrial migrations have been severely reduced and a quarter of the migrating s...

The annual migration of the Monarch butterfly (Danaus plexippus) from eastern North America to central Mexico is one of nature's most inspiring spectacles. Recent studies including one in BMC Biology, have begun to dissect the molecular and neurogenetic basis for this most complex behavior.

Many migrations are temporary – a fact that has often been ignored in the economic literature on migration. Such omission may be serious in that expected migration temporariness can impart a distinct dynamic element to immigrants’ economic behavior, generating possible consequences for non-migrants in both home and host countries. In this paper we provide a thorough examination of the various a...