A young male who presented with isolated bihormonal gonadotrophin deficiency is described, Basal levels of LH and FSH were low and there was no response to clomiphene citrate or LHRH. The remaining anterior pituitary function was intact. The administration of a combination of human menopausal gonadotrophin and human chorionic gonadotrophin caused testicular maturation with spermatogenesis and f...

We described 59-year-old men with history of secondary/tertiary hypogonadism, without primary hypothyroidism, elevated prolactin or hemochromatosis structurally intact hypothalamo- hypophyseal (HT-HP) axis who was diagnosed in 2017. He treated by different physicians Testosterone intramuscular injections, hCG injections and combination FSH injections. The patients wanted to have another child t...

428 receptors than the myometrium4. However, in younger women, besides its agonist action, these drugs may also block the estrogen receptors in the hypothalamus leading to intense output of gonadotrophins which lead to ovarian stimulation and growth of myoma. An increase in cervical and endometrial polyps with neoplastic change in the endometrium has been reported. The potential for similar pro...