نتایج جستجو برای: closed in vitro dissolution test method
تعداد نتایج: 17333692 فیلتر نتایج به سال:
پژوهش های پیشین نشاندهنده اثر ضد ویروسی فراورده های تهیه شده از گیاه سرخارگل و میوه آقطی سیاه بر ویروس های انسانی جنس a و b در محیط کشت سلولی و در شرایط in vitro می باشند. در این تحقیق اثر ضد ویروسی دو عصاره استاندارد شده تجاری echinacea purpurea (ef) و sambucus nigra (sam) در مقایسه با داروی آمانتادین بر ویروس آنفلوانزای پرندگان h9n2 در شرایط in vivo و in vitro بررسی شده است. برای مطالعه اثر...
in solvo-hydrothermal method, xrd pattern was indicated presence of intermediate of ammonium octatmolybdate and ammonium tetramolybdate, which were changed to stble phase of ?-moo3 annealing. sem images were indicated nanoparticle with semispheical morphology and tem image was demonstrated nanoparticles with a diameter size of 25nm. also in impregnate method. the xrd pattern was shown high crys...
one of the most important goals for increasing recognition and treatment revenue is transmitting vital data to medical care team, more quickly. nowadays, use of new technologies for transmitting data will deploy more and more daily. in this article, for transmitting electrocardiogram, first we code the signal into a suite of codes, then we will use bluetooth technology to transmit data from off...
Ibuprofen solid dispersions were prepared by the solvent and fusion-solvent methods using polyethylene glycol (PEG), polyvinylpyrrolidone (PVP), eudragit RS PO, eudragit RL PO and hydroxypropylmethylcellulose (HPMC) as carriers to improve physicochemical characteristics of ibuprofen. The prepared solid dispersions were evaluated for the flowability, solubility characteristics and dissoluti...
The bioequivalence of three chemically equivalent paracetamol generic Mexican products (500 mg tablets) was evaluated in 12 healthy volunteers using the American innovator product (Tylenol, McNeil, Fort Washington, PA), as the reference. Single oral doses of each product were administered at 1-week intervals using a 4 x 4 Latin square design balanced for the first residual effect. The total amo...
INTRODUCTION: Dissolution is the required characterization test to evaluate new materials for transdermal drug delivery [1]. However the conventional dissolution tests, recommended by United State Pharmacopeia (USP), cannot provide results with good correlation with in vivo drug release, especially for patches that mainly depends on skin resistance to drug diffusion [2]. Other dissolution metho...
BACKGROUND Current scientific evidence indicates that anemia in pregnancy, regardless of severity, is associated with an increased risk of maternal and fetal mortality. There is little published information about the bioavailability and bioequivalence of formulations containing both iron and folic acid. However, in vitro dissolution studies can provide important information on the likely relati...
The aim of the present study was to develop a single unit, site-specific matrix tablets of aceclofenac allowing targeted drug release in the colon with a microbially degradable polymeric carrier, chondroitin suphate (CS) and to coat the optimized batches with a pH dependent polymeric. The tablets were prepared by wet granulation method using starch mucilage as a binding agent and HPMC K-100 ...
Introduction In recent years,there has been a strong push to identify bioavailability problems of a drug formulation based on the results of appropriately designed dissolution experiments. Particularly for immediate release (IR) dosage forms, the paddle apparatus has evolved as the method of choice for this purpose (1,2). However,standard paddle experiments require both large volumes of test me...
To ensure that a drug product will meet standards for identity, strength and stability as specified in the United States Pharmacopedia and National Formulary (USP/NF), it needs to pass a number of tests such as the content uniformity test and dissolution test at various stages of the manufacturing process. The sponsors usually have in-house specification limits based on some lower bounds of the...
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