Lactic acid bacteria (LAB) are a promising solution to reduce exposure to dietary mycotoxins because of the unique mycotoxin decontaminating characteristic of some LAB. Ochratoxin A (OTA) is one of the most prominent mycotoxins found in agricultural commodities. The present work reports on the ability of Pediococcus parvulus strains that were isolated from Douro wines that spontaneously underwe...

Ochratoxin A (OTA), mainly produced by Aspergillus and Penicillum species, is one of the most important mycotoxin contaminants in agricultural products. It is detrimental to human health because of its nephrotoxicity, hepatotoxicity, carcinogenicity, teratogenicity, and immunosuppression. OTA structurally consists of adihydrocoumarin moiety linked with l-phenylalanine via an amide bond. OTA bio...

Ochratoxin A (OTA) is a mycotoxin produced by several fungi. Many foods can be contaminated by OTA, which is consequently found in the blood of humans and animals. It is known that OTA accumulates in the brain. The aim of this study was to investigate the effects of OTA on the brain. For this purpose, the effect of OTA on N-methyl-D-aspartate (NMDA) receptor subunits 2A (NR2A) and 2B (NR2B) in ...

This paper presents a low-power fractional-N synthesizer for BLE with gate-switching charge pump (CP) and high-speed prescaler. To reduce the current mismatch under low supply voltage, master-slave rail-to-rail operational trans-conductance amplifier (OTA) structure is employed to CP; Current self-matching technique guarantees charging equal discharging current. The embedded logic gates power s...

A continuous-time common-mode feedback (CMFB) circuit for low-power, area-constrained neural recording amplifiers is proposed. The proposed CMFB compact; it can be realized by simply replacing passive components with transistors in a low-noise folded cascode operational transconductance amplifier (FC-OTA) that one of the most widely adopted OTAs amplifiers. also consumes no additional power, i....

A two stage sub-μW Inverter-based switched-capacitor amplifier-filter is presented which is capable of amplifying both spikes and Local Field Potentials (LFP) signals. Here we employ a switched capacitor technique for frequency tuning and reducing of 1/f noise of two stages. The reduction of power consumption is very necessary for neural recording devices; however, in Switched Capacitor (SC) ci...

Recent developments in portable applications and systems have lead to a significant in wireless standards. Therefore, cost efficiency of CMOS technology implementation has been greatly enhanced with the emergence of multi-mode wireless applications. Now multimode/multi-band receivers are designed based on the scheme of reuse[1]-[3]. They avoid using multiple chipsets and can be made tunable whi...

Ochratoxin A (OTA) is a nephrotoxin and carcinogen that is associated with Balkan endemic nephropathy and urinary tract tumors. OTA crosses the placenta and causes adducts in the liver and kidney DNA of newborns. Because the testis and kidney develop from the same embryonic tissue, we reasoned that OTA also may cause adducts transplacentally in the testis. We tested the hypothesis that acute ex...

Ochratoxin A (OTA) is a natural contaminant that has displayed nephrotoxicity and hepatotoxicity in mammals. It contaminates a great variety of foodstuffs and threatens people's lives. The molecular mechanism of OTA-induced toxicity has been studied since 1965. Moreover, epigenetic mechanisms are also studied in OTA-induced toxicity. Additionally, the mode of OTA epigenetic research has been ad...

Background: Ochratoxin A (OTA) and Aflatoxin B1 (AFB1) are toxic secondary  metabolites produced by certain mold species. In this primarily survey, we examined the OTA and AFB1 contamination of pearl millet grains distributed in Tunisia. Methods: Twenty-five pearl millet (Pennisetum glaucum L.) samples from different regions of Tunisia were analyzed by High Performance Liquid Chromatography co...