نتایج جستجو برای: cmt 4a
تعداد نتایج: 7820 فیلتر نتایج به سال:
Background: In prior studies, there has been no report of clinical observation postoperative reconnection the sternocleidomastoid muscle (SCM) in children with congenital muscular torticollis (CMT). Therefore, objective this study is to investigate factors associated SCM CMT, and provide evidence.
Mutations in GDAP1, the ganglioside-induced differentiation-associated protein 1 gene, cause Charcot-Marie-Tooth (CMT) type 4A, a severe autosomal recessive form of neuropathy associated with either demyelinating or axonal phenotypes. Here, we demonstrate that GDAP1 has far greater expression in neurons than in myelinating Schwann cells. We investigated cell localization of GDAP1 in a human neu...
INTRODUCTION The topographic mapping is useful for monitoring patients for the development of macular edema and following the resolution of edema after laser treatment. OBJECTIVES To evaluate the usefulness of optical coherence tomography (OCT) for mapping of macula after laser therapy in clinically significant macular edema (CSME). MATERIALS AND METHODS A prospective study was carried out ...
OBJECTIVE To evaluate the use of palpation of the coccyx (the coccygeal movement test, CMT) as a possible objective screening tool for the assessment of adequate localization of the pelvic floor muscles (PFMs). SUBJECTS AND METHODS Twenty-four healthy female volunteers, known to be able to locate their PFMs, were given instructions (allocated at random) to perform a 'correct contraction', 'st...
BACKGROUND Charcot-Marie-Tooth disease (CMT) is a hereditary peripheral neuropathy; symptoms include distal wasting and weakness, usually with some sensory impairment. The clinical course is typically benign and the disease is not life threatening; however, in some cases, severe phenotypes include serious respiratory distress. CASE REPORT Here we describe a 45-year-old woman with a long cours...
BACKGROUND The limited within-breed genetic heterogeneity and an enrichment of disease-predisposing alleles have made the dog a very suitable model for the identification of genes associated with risk for specific diseases. Canine mammary cancer is an example of such a disease. However, the underlying inherited risk factors for canine mammary tumours (CMTs) are still largely unknown. In this st...
In the assessment of respiratory muscle function balloon catheters have been widely used for pressure measurements. However, this type of investigation is poorly tolerated by acutely ill patients. This study assessed the performance of a possible alternative, a catheter-mounted miniature pressure transducer (CMT). The assessment consisted of a laboratory study of the linearity, frequency respon...
A series of experiments in DBA/2J mice evaluated the biological and pharmacokinetic interactions of the alkylating agent cyclophosphamide (CTX) and the histamine-H2 antagonists cimetidine (CMT) and ranitidine (RNT). Doses were adjusted to approximate human dose levels: 100 mg/kg for CMT; and 25 mg/kg for RNT. CMT reduced the survival of normal (bone marrow stem cell) colony forming units in a d...
A series of experiments in DBA/2J mice evaluated the biological and pharmacokinetic interactions of the alkylating agent Cyclophosphamide (CIA)and the histamine-H; antagonistscimetidine(CMT)and ranitidine (RNT). Doses were adjusted to approximate human dose levels: 100 mg/ kg for CMT; and 25 mg/kg for RNT. CMT reduced the survival of normal (bone marrow stem cell) colony forming units in a dose...
PURPOSE To identify baseline characteristics that predict the number of treatments with intravitreal triamcinolone acetonide (IVTA) plus laser photocoagulation needed to treat diabetic macular edema over a 2-year period. METHODS Individual data from 42 eyes of 42 participants treated with IVTA plus laser photocoagulation for diabetic macular edema during a prospective, randomized, double-mask...
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