OBJECTIVES/HYPOTHESIS To describe cochlear nerve deficiency and abnormalities of the internal auditory canal (IAC) associated with CHARGE (coloboma, heart defects, atresia choanae, retardation of growth and/or development, genital hypoplasia, and ear anomalies and/or deafness) syndrome. STUDY DESIGN Case series. METHODS In a tertiary children's hospital, children with CHARGE syndrome were e...

UNLABELLED An audiogram is not sufficient to indicate cochlear dead regions. AIM To investigate cochlear dead regions in sensorineural hearing loss subjects using the TEN test. SITE: CEDALVI/ HRAC-USP-Bauru/Sao Paulo/Brazil, August 2003 to February 2004. STUDY DESIGN A contemporary cross-sectional cohort study. MATERIAL AND METHODS The TEN test was applied in three groups: G1(5 women with...

Regulation of cochlear blood flow is critical for hearing due to its exquisite sensitivity to ischemia and oxidative stress. Many forms of hearing loss such as sensorineural hearing loss and presbyacusis may involve or be aggravated by blood flow disorders. Animal experiments and clinical outcomes further suggest that there is a gender preference in hearing loss, with males being more susceptib...

Hearing thresholds in elderly humans without a history of noise exposure commonly show a profile of a flat loss at low frequencies coupled with a loss that increases with frequency above approximately 2 kHz. This profile and the relatively robust distortion product otoacoustic emissions that are found in elderly subjects challenge the common belief that age-related hearing loss (presbyacusis) i...

Prolonged Exposure to Industrial Noise: Cochlear Pathology does not Correlate with the Degree of Permanent Threshold Shift, but is Related ́ ́ to Duration of Exposure: Mariola SLIWINSKA-KOWALSKA, et al. Department of Physical Hazards, The Nofer Institute of Occupational Medicine—It has been shown that the damaging effects of noise on the mammalian inner ear strongly depend upon parameters of exp...

The decision of whether to perform cochlear implantation is crucial because cannot be reversed without harm. aim the study was compare model-predicted time–place representations auditory nerve (AN) firing rates for normal hearing and impaired with a view towards personalized indication implantation. AN 1024 virtual subjects wide variety different types degrees impairment were predicted. A refer...

The most dramatic progress in the restoration of hearing takes place in the first months after cochlear implantation. To map the brain activity underlying this process, we used positron emission tomography at three time points: within 14 days, three months, and six months after switch-on. Fifteen recently implanted adult implant recipients listened to running speech or speech-like noise in four...

We examined a 38-year-old male with syringohydromyelia and concomitant symptoms suggestive of intracranial hypertension including unilateral low-frequency sensorineural hearing loss and objective pulsatile tinnitus. The tinnitus was heard by the authors (through a hearing aid stethoscope tube), measured objectively (with a probe microphone), measured subjectively (as minimum masking levels and ...

INTRODUCTION  Cochlear implants may guarantee sound perception and the ability to detect speech at a close-to-normal hearing intensity; however, differences have been observed among implantees in terms of performance on discrimination tests and speech recognition. OBJECTIVE  To identify whether patients with post-meningitis deafness perform similarly to patients with hearing loss due to other...

OBJECTIVE The trauma caused during cochlear implant insertion can lead to cell death and a loss of residual hair cells in the cochlea. Various therapeutic approaches have been studied to prevent cochlear implant-induced residual hearing loss with limited success. In the present study, we show the efficacy of mild to moderate therapeutic hypothermia of 4 to 6 °C applied to the cochlea in reducin...