نتایج جستجو برای: cognition disorders

تعداد نتایج: 711786  

2011
P. Read Montague Raymond J. Dolan Karl J. Friston Peter Dayan

P. Read Montague, Raymond J. Dolan, Karl J. Friston and Peter Dayan 1 Virginia Tech Carilion Research Institute and Department of Physics, Virginia Tech, 2 Riverside Circle, Roanoke, VA 24016, USA 2 Wellcome Trust Centre for Neuroimaging, University College London, 12 Queen Square, London, WC1N 3BG, UK 3 Gatsby Computational Neuroscience Unit, Alexandra House, 17 Queen Square, London, WC1N 3AR, UK

Journal: :Learning & memory 2013
Sven Parkel Jose P Lopez-Atalaya Angel Barco

Recent research indicates that epigenetic mechanisms and, in particular, the post-translational modification (PTM) of histones may contribute to memory encoding and storage. Among the dozens of possible histone PTMs, the methylation/demethylation of lysines in the N-terminal tail of histone H3 exhibits particularly strong links with cognitive abilities. First, the persistence and tight associat...

Journal: :Human molecular genetics 2006
Patrice Roll Gabrielle Rudolf Sandrine Pereira Barbara Royer Ingrid E Scheffer Annick Massacrier Maria-Paola Valenti Nathalie Roeckel-Trevisiol Sarah Jamali Christophe Beclin Caroline Seegmuller Marie-Noëlle Metz-Lutz Arnaud Lemainque Marc Delepine Christophe Caloustian Anne de Saint Martin Nadine Bruneau Danièle Depétris Marie-Geneviève Mattéi Elisabeth Flori Andrée Robaglia-Schlupp Nicolas Lévy Bernd A Neubauer Rivka Ravid Christian Marescaux Samuel F Berkovic Edouard Hirsch Mark Lathrop Pierre Cau Pierre Szepetowski

The rolandic and sylvian fissures divide the human cerebral hemispheres and the adjacent areas participate in speech processing. The relationship of rolandic (sylvian) seizure disorders with speech and cognitive impairments is well known, albeit poorly understood. We have identified the Xq22 gene SRPX2 as being responsible for rolandic seizures (RSs) associated with oral and speech dyspraxia an...

Journal: :Journal of neurology, neurosurgery, and psychiatry 2014
Fiona Kumfor Muireann Irish Cristian Leyton Laurie Miller Suncica Lah Emma Devenney John R Hodges Olivier Piguet

BACKGROUND AND PURPOSE Behavioural-variant frontotemporal dementia (bvFTD) and Alzheimer's disease (AD) patients experience behavioural and emotion recognition alterations, yet understanding of how socioemotional processing is affected with disease progression is minimal. Additionally, evidence suggests that bvFTD patients with limited brain atrophy on neuroimaging at presentation (bvFTD-la) ha...

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