N-cadherin, a member of the Ca(2+)-dependent cell adhesion molecule family plays essential roles in morphogenesis and histogenesis. N-cadherin has been shown in vitro to promote myoblast fusion and neurite outgrowth. We report here the cellular localization of N-cadherin during development and regeneration of the chick neuromuscular system. N-cadherin was uniformly expressed along the surface o...

background & objectives: oral submucous fibrosis (osmf) is a condition where excessive deposition of dense collagen fibers occurred in the connective tissue of oral mucosa. an alteration of collagen necessitates an in depth understanding of collagen in oral tissues as no breakthrough studies have been reported. therefore the aim was to correlate the clinical, functional and histopathologica...

The effect of cooking on pH, juiciness, instrumental colour and microstructural properties chicken breast meat was investigated. Industrial skinless samples were purchased, frozen sliced into dimensions , thawed cooked by air frying (AF), baking (BK), deep fat (DF) grilling (GR) at 170, 180 1900C for 0, 4, 8, 12 16 min. pH value the increased from 6.05 to 6.25. Cooking methods, temperatures tim...

Background An intact composition of extracellular matrix (ECM) collagens, proteoglycans and elastic fibres are responsible for the constitutional strength of tendons and ligaments [1,2]. It is known that pathophysiological changes in the ECM could lead to reduced extension properties and diminished capacity of energy absorption of ligaments and tendons and could promote diseases like patellar t...

Time-lapse motion picture studies were carried out on isolated fowl embryo osteoclasts in vitro, the cells have an extremely active ruffled border, and show vigorous pinocytotic activity. Electron microscope studies on osmium-fixed cells showed that the pinocytotic vacuoles contained bone salt crystals (as well as material which could not be identified on morphological grounds), and that the fo...

A case of pachydermoperiostosis characterised by the presence of finger clubbing, periostosis, sweating of hands and feet is described. Modifications of capillaroscopic pattern and of arteriovenous anastomoses are reported. The periungual border and finger tip tissue showed diffuse endothelial hyperplasia, hyalinosis, and sclerosis with packing of collagen fibres. Electron microscopy showed hyp...

An argument is presented for discontinuing the term ‘contraction’ when describing the so-called active state of muscles and replacing it with a neutral term such as ‘hardening’. The opposite state of the muscle would be called ‘softening’. Hardening as a so-called active state of a muscle may be accompanied by lengthening, shortening, or no dimensional change in the anatomical muscle, depending...

BACKGROUND The aetiology and pathogenesis of abdominal wall hernia formation is complex. Optimal treatment of hernias depends on a full understanding of the pathophysiological mechanisms involved in their formation. The aim of this study was to review the literature on specific collagen alterations in abdominal wall hernia formation. METHODS A computer-assisted search of the medical databases...

Native and cross-linked rat tail tendon collagen was irradiated with high energy electrons up to a maximum dose of 100 x io J kg" (100 Mrd). Fibres irradiated dry showed greater damage when examined in the electron microscope using negative staining techniques than those irradiated wet. Cross-linking with glutaraldehyde prior to irradiation resulted in the band structure being preserved even at...