AIM To evaluate fundamental cell functions, such as adhesion, IL-6 production and proliferation of human gingival keratinocytes cultured on a newly engineered collagen matrix (CM-10826) and to assess the degree of specific biocompatibility of this new device. MATERIALS AND METHODS Primary cultures of human keratinocytes were derived "in vitro" from biopsies of independent donors. Their true e...

Objectives: The purpose of this study was to evaluate the effect of low dose doxycycline and atorvastatin on gingival inflammation and alveolar bone loss in an experimental model of periodontitis in rats. Methods: Forty male Sprague Dawley rats were divided into four study groups as follows: (I) experimental periodontitis control, (II) rats with periodontitis treated with low dose atorvastatin...

introduction: striae distensae (sd) are a frequent skin condition for which treatment remains a challenge. the 1540-nm non-ablative fractional laser (star lux 500) has been shown to improve atrophic scars by increasing the amount of dermal collagen. to assess the safety and efficacy of the star lux 500 laser in the treatment of mature hypopigmented striae in persian people (striae alba). method...

Chronic periodontitis is characterized by dense infiltrations of B and T lymphocytes within the gingival connective tissue. Distinct anaerobic gram-negative bacteria as well as autoimmunity to collagen have been reported to play a role in the etiology and the pathogenesis of this disease. Here we describe the cloning and characterization of CD4+ and CD8+ T lymphocytes isolated from inflamed gin...