Underwater geoarchaeological research in Apalachee Bay, in the northeastern Gulf of Mexico off northwest Florida, has enabled the reconstruction of portions of the karstcontrolled paleodrainage system, the discovery of several inundated prehistoric archaeological sites, and the exposure of sediments accumulated during the drowning of the continental shelf. Diagnostic artifacts discovered at the...

Post-translational modification by the small ubiquitin-like modifier (SUMO) is an important mechanism regulating protein function. Identification of SUMO conjugation sites on substrates is a challenging task. Here we employed a proteomic method to map SUMO acceptor lysines in budding yeast proteins. We report the identification of 257 lysine residues where SUMO is potentially attached. Amongst ...

Researchers at the Geoengineering and Mineral Processing Study Centre of the Italian Research Council, have developed a database system integrated with a GIS (Geographical Information System),jor data collection on operational or closed waste disposal sites. This paper describes the objectives of the system, the data organisation, the structure of the database, the characteristics and functiona...

Refdbms is a database system for sharing bibliographic references among many users at sites on a wide-area network such as the Internet. This paper describes our experiences in building and using refdbms for the last two years. It summarizes the collection of facilities that refdbms provides, and gives detailed information on how well refdbms functions as a collaborative, wide-area, distributed...

Engineering applications for the World Wide Web is becoming increasingly difficult. Web engineers are forced to contend with a heterogeneous collection of Web services, which differ in terms of available bandwidth, display quality and connection type. Faced with these sources of heterogeneity, Web engineers often publish separate, typically redundant Web sites, each of which is tailored to a sp...

We prove a version of the associated sheaf functor theorem in Algebraic Set Theory. The proof is established working within a Heyting pretopos equipped with a system of small maps satisfying the axioms originally introduced by Joyal and Moerdijk. This result improves on the existing developments by avoiding the assumption of additional axioms for small maps and the use of collection sites.

NCBI's Conserved Domain Database (CDD) is a collection of multiple sequence alignments and derived database search models, which represent protein domains conserved in molecular evolution. The collection can be accessed at http://www.ncbi.nlm.nih.gov/Structure/cdd/cdd.shtml, and is also part of NCBI's Entrez query and retrieval system, cross-linked to numerous other resources. CDD provides anno...

Compiled by three academic librarians, Digital Collections Worldwide provides an exhaustive and valuable annotated listing of the world's most authoritative and comprehensive digital collections. The authors describe over 1,400 digital collections and include an extensive subject index. The Internet is full of digital collections that allow users to easily access information quickly, but it can...