The proposed study is a pre and post treatment study to determine whether commonly used laxative-treatment for clozapine-treated psychiatric inpatients affects gastrointestinal motility (as measured by radiopaque marker (ROM) transit studies). This is a follow up study to the ‘Colonic transit studies to measure gastrointestinal motility in antipsychotic-treated patients’ study described in a pr...

We read with interest the paper by Carmona et al. in relation to patients consulting for constipation in Mexico. 1 This paper provides further information to a problem in Mexico that has a prevalence ranging from 7 to 19%. 2 However, we must comment on two aspects. First, the Rome III Questionnaire (RIIIQ) was used to diagnose Chronic Constipation (CC) and IBS-C, and although the authors state ...

Objective. To investigate the effects and safety of the aqueous extract of the dried, immature fruit of Poncirus trifoliata (L.) Raf., known as Poncirus fructus (PF), in spinal cord injury (SCI) patients with neurogenic bowel. Methods. Thirty-one SCI patients with neurogenic bowel were recruited. Patients were evaluated based on clinical information, constipation score, Bristol Stool Form Scale...

Summary Linked to the growing obesity epidemic, demand for bariatric and metabolic surgery has increased, most common procedures being sleeve gastrectomy Roux-en-Y gastric bypass. Originally, were described as purely restrictive, malabsorptive, or combined restrictive–malabsorptive limiting food intake, nutrient absorption, both. Nowadays, anatomical alterations are known affect gastro...

BACKGROUND Data on small intestinal transit time in healthy children are lacking, and normal values for gastric emptying and colonic transit time are sparse. Conventional methods, including radiopaque markers, scintigraphy, and PillCam™ involve radiation or require the child to swallow a large pill. The minimally invasive, radiation-free Motility Tracking System-1 (MTS-1) has been introduced fo...

Twenty healthy subjects eating normal diets made repeated five-day stool collections, the 10 females making their collections in four to six successive weeks. In most subjects there were striking variations in transit time, measured by Hinton's method. The variability of average faecal wet and dry weight, faecal volume, and the frequency of defaecation was equally great, suggesting that the tra...

BACKGROUND Yacon is a root crop which contains high amounts of fructooligosaccharides (FOS). The aim of this study was to investigate the effects of yacon syrup on colon transit time in healthy volunteers. METHODS In a placebo-controlled, double-blind study yacon was administered to 16 healthy individuals (8 males, 8 females) in a dose of 20 g daily (equal to 6.4 g FOS) in a 2-week crossover ...