Human rhinovirus strains differ greatly in their virulence, and this has been correlated with the differing substrate specificity of the respective 2A protease (2Apro). Rhinoviruses use their 2Apro to cleave a spectrum of cellular proteins important to virus replication and anti-host activities. These enzymes share a chymotrypsin-like fold stabilized by a tetra-coordinated zinc ion. The catalyt...

We prove that, for positive integers m and b, the number of simultaneous solutions in positive integers to x2− (4m2−1)y2 = 1, y2−bz2 = 1 is at most one.

Given two strings X and Y of N and M characters respectively, the Longest Common Sub-sequence LCS Problem asks for the longest sequence of non-contiguous matches between X and Y. Let LN be the length of a LCS of two random strings of size N. Using extensive Monte Carlo simulations for this problem, we nd a nite size scaling law of the form ELN=N = S + AS=ln N p N + :::, where S and AS are const...

After the successful conclusion of the CLEO III phase, the CLEO experiment at the Cornell electron positron storage ring CESR is preparing for its transition to CLEO-c. This new program contains a wide array of Physics studies at e + e − collisions at center of mass energies between 3 GeV and 5 GeV that will provide new insights into QCD. Because the existing Silicon Vertex Detector needed to b...

Generalizations of the three main equations of quantum physics, namely, the Schrödinger, Klein-Gordon, and Dirac equations, are proposed. Nonlinear terms, characterized by exponents depending on an index q, are considered in such a way that the standard linear equations are recovered in the limit q→1. Interestingly, these equations present a common, solitonlike, traveling solution, which is wri...

We classify all functions satisfying non-trivial families of PVIα equations. It turns out that, up to an Okamoto equivalence, there are exactly four families parameterized by affine planes or lines. Each affine space is generated by points of ”geometric origin”, associated either to deformations of elliptic surfaces with four singular fibers, or to deformations of three-sheeted covers of P1 wit...

The longest arc-preserving common subsequence problem is an NPhard combinatorial optimization problem from the field of computational biology. This problem finds applications, in particular, in the comparison of arc-annotated Ribonucleic acid (RNA) sequences. In this work we propose a simple, hybrid evolutionary algorithm to tackle this problem. The most important feature of this algorithm conc...

This paper studies the diamond problem in the context of delegation-based object systems. The diamond problem occurs when the same ancestor is inherited multiple times via different inheritance paths. The challenge is that replication and sharing of distinct attributes of the common ancestor must be simultaneously supported. We illustrate the relevance of the diamond problem by showing that it ...

CONTEXT Health care professionals advocate that athletes who are susceptible to exercise-associated muscle cramps (EAMCs) should moderately increase their fluid and electrolyte intake by drinking sport drinks. Some clinicians have also claimed drinking small volumes of pickle juice effectively relieves acute EAMCs, often alleviating them within 35 seconds. Others fear ingesting pickle juice wil...

Potential Solution? March/April 2007 Timothy Hoffmann Metromedia International Group, Inc.’s board of directors faced a perplexing dilemma. Approached with an attractive offer from a potential purchaser, the board wanted to sell the corporation’s primary asset and cease operations. In order to consummate the transaction, however, Delaware law and the company’s certificate of incorporation requi...