The reaction mechanism of the Cu+-catalyzed introduction two all-carbon-substituted stereocenters in an ynamide system using a Grignard reagent, zinc carbenoid, and aldehyde, was investigated density-functional theory. In contrast to formation organocopper(I) compound subsequent carbocupration reaction, previously postulated as initial step, proved instead proceed through complexation substrate...

The title compound, C8H12S2 (trivial name DTCDD), was obtained as a side product of the reaction between cis-1,4-di-chloro-but-2-ene and sodium sulfide. The asymmetric unit consists of one-quarter of the mol-ecule (S site symmetry 2) and the complete mol-ecule has 2/m (C 2h ) point symmetry with the C=C bond in an E conformation. The geometry of the title compound is compared to those of a chlo...

due to the antitumor activity of gallium mal complex, as well as recent findings on new targeted biomolecules in malignant cells through this complex, the development of radiolabeled gallium complex for future imaging studies was targeted. ga-67 labeled 3-hydroxy-2-methyl-4h-pyran-4-onate (ga-67 mal) was prepared using freshly prepared ga-67 chloride and 3-hydroxy-2-methyl-4h-pyran-4-onate in a...

We synthesized the novel histidine complex of uranium(IV). A 1:3 mole ratio was found between metal and ligand by method, while –NH2 –COO– groups behave as coordinating sites. The IR spectra confirmed lone pair donating or elemental analysis stoichiometry. bathochromic shift with an increase in optical density UV-Visible range indicated that compound its central ion hold uniform electronic char...

A reaction between [(COD)IrCl]2 (COD is cyclo-octa-1,5-diene), HCl and indene failed to provide the hoped for chlorido-indenyliridium dimer, but instead produced the title compound, [IrCl3(CH3CN)(C8H12)], which is an octa-hedral complex of iridium(III) with a chelating cyclo-octa-1,5-diene ligand, three chloride ligands in a fac arrangement, and one aceto-nitrile ligand. Attempts to devise a ra...

We report the preparation of a dicobalt compound with two singly proton-bridged cobaloxime units linked by a central [BO4] bridge. Reaction of a doubly proton-bridged cobaloxime complex with trimethyl borate afforded the compound in good yield. Single-crystal X-ray diffraction studies confirmed the bridging nature of the [BO4] moiety. Using electrochemical methods, the dicobalt complex was foun...

The 7-(4-aminomethyl-1H-1,2,3-triazol-1-yl) analogue of kabiramide C (5) was synthesized by using the Mitsunobu reaction and 1,3-dipolar cycloaddition. This compound and the intermediate compounds 2 and 4 were shown to bind tightly to G-actin in a 1:1 complex and exhibited the same degree of cytotoxicity as 1. Compound 5 serves as a key intermediate for the synthesis of actin-directed optical p...

Copper nanoparticles prepared from copper acetylacetonate complex or acetate show significant differences in terms of reaction mechanism and further catalytic transformation oleylamine.

J.t is well established thait both the an ti body de­ficiency and the reaction beru,een antigen and _ant.i­ hody cause many diseases Then there is antibody ·c1e­,ficiency the resulting disease is called antibody defi­ciency disease; and when the contact of antigen vih antibody produces the disease or the complex of anti­gen with antibody precipitates and causes tissue dama­ge the ,lesion is cal...